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Clinical Utility of Preoperative Vitamin D3 Injection for Preventing Transient Hypocalcemia after Total Thyroidectomy
DC Field | Value | Language |
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dc.contributor.author | 강상욱 | - |
dc.contributor.author | 남기현 | - |
dc.contributor.author | 이잔디 | - |
dc.contributor.author | 이초록 | - |
dc.contributor.author | 정웅윤 | - |
dc.contributor.author | 정종주 | - |
dc.date.accessioned | 2021-04-29T17:01:25Z | - |
dc.date.available | 2021-04-29T17:01:25Z | - |
dc.date.issued | 2021-02 | - |
dc.identifier.issn | 1687-8337 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/182140 | - |
dc.description.abstract | Background: Postoperative transient hypocalcemia (TH) is a common complication of total thyroidectomy. This retrospective study evaluated the clinical utility of preoperative vitamin D3 injection for the prevention of TH after total thyroidectomy. Methods: We included 2294 patients who underwent total thyroidectomy from January 2015 until October 2018 and retrospectively analyzed their data by complete chart review at our hospital. The patients were divided into two groups: vitamin D3 injection (VDI; n = 342) and vitamin D3 noninjection (VDN; n = 1952). TH was defined as serum calcium <8.2 mg/dL and signs or symptoms of hypocalcemia. Results: The mean preoperative serum 25-hydroxyvitamin D (25-OHD) levels of the VDI group were significantly lower than those of the VDN group (16.5 ± 6.9 ng/mL vs 19.4 ± 8.7 ng/mL, p < 0.001). Multivariate analysis indicated that the significant risk factors of TH include vitamin D noninjection (hazard ratio (HR): 1.717, 95% confidence interval (CI): 1.282-2.300, p < 0.001), male gender (HR: 1.427, 95% CI: 1.117-1.822, p = 0.004), and capsular extension (HR: 1.273, 95% CI: 1.011-1.603, p = 0.040). Conclusions: Preoperative vitamin D3 injection significantly contributed to the prevention of TH after total thyroidectomy. Further prospective or multicenter studies must be conducted to determine the effect of vitamin D3 injection. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Hindawi Pub. Corp. | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF ENDOCRINOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Clinical Utility of Preoperative Vitamin D3 Injection for Preventing Transient Hypocalcemia after Total Thyroidectomy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Kwangsoon Kim | - |
dc.contributor.googleauthor | Cho Rok Lee | - |
dc.contributor.googleauthor | Sang-Wook Kang | - |
dc.contributor.googleauthor | Jandee Lee | - |
dc.contributor.googleauthor | Jong Ju Jeong | - |
dc.contributor.googleauthor | Kee-Hyun Nam | - |
dc.contributor.googleauthor | Woong Youn Chung | - |
dc.identifier.doi | 10.1155/2021/6683089 | - |
dc.contributor.localId | A00032 | - |
dc.contributor.localId | A01245 | - |
dc.contributor.localId | A03066 | - |
dc.contributor.localId | A03256 | - |
dc.contributor.localId | A03674 | - |
dc.contributor.localId | A03722 | - |
dc.relation.journalcode | J01109 | - |
dc.identifier.eissn | 1687-8345 | - |
dc.identifier.pmid | 33628238 | - |
dc.contributor.alternativeName | Kang, Sang Wook | - |
dc.contributor.affiliatedAuthor | 강상욱 | - |
dc.contributor.affiliatedAuthor | 남기현 | - |
dc.contributor.affiliatedAuthor | 이잔디 | - |
dc.contributor.affiliatedAuthor | 이초록 | - |
dc.contributor.affiliatedAuthor | 정웅윤 | - |
dc.contributor.affiliatedAuthor | 정종주 | - |
dc.citation.volume | 2021 | - |
dc.citation.startPage | 6683089 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF ENDOCRINOLOGY, Vol.2021 : 6683089, 2021-02 | - |
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