Cited 36 times in
Chronic progression of cardiac surgery associated acute kidney injury: Intermediary role of acute kidney disease
DC Field | Value | Language |
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dc.contributor.author | 곽영란 | - |
dc.contributor.author | 송종욱 | - |
dc.contributor.author | 심재광 | - |
dc.contributor.author | 이삭 | - |
dc.contributor.author | 조진선 | - |
dc.contributor.author | 최낙철 | - |
dc.date.accessioned | 2021-04-29T17:00:52Z | - |
dc.date.available | 2021-04-29T17:00:52Z | - |
dc.date.issued | 2021-02 | - |
dc.identifier.issn | 0022-5223 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/182138 | - |
dc.description.abstract | Objective: The association between acute kidney injury (AKI) and chronic kidney disease (CKD) remains elusive in cardiac surgery. We investigated the association between postoperative AKI and CKD development, emphasizing the intermediary role of acute kidney disease (AKD), in patients undergoing valvular heart surgery. Methods: We assessed the occurrence of postoperative AKI (7 days postsurgery), AKD (3 months postsurgery), and CKD (12 months postsurgery) in 1386 patients. The primary outcome was the development of AKD and CKD according to AKI occurrence. Relevant risk factors of AKI, AKD, and CKD were identified through multivariable regression analysis. Results: AKI occurred in 23.9% of patients with normal preoperative renal function. Even with early recovery of renal function within 3 days, AKI increased the risk of AKD (odds ratio [OR], 3.21; 95% confidence interval [CI], 1.98-5.20, P < .001) and CKD (OR, 2.86; 95% CI, 1.68-4.86, P < .001), whereas persistent AKI further increased the risk of AKD (OR, 12.07; 95% CI, 5.56-26.21, P < .001) and CKD (OR, 10.54; 95% CI, 4.01-27.76, P < .001). We also found these relationships in patients with pre-existing renal dysfunction. Multivariable analysis identified 3-month postoperative heart failure and high right ventricular systolic pressure as independent risk factors for CKD. Conclusions: Even after early recovery, postvalvular heart surgery AKI was associated with increased risk of CKD via AKD in a graded manner related to AKI severity and persistence. Postoperative cardiac dysfunction assessed 3 months postsurgery also significantly influenced CKD development, indicating a need for close follow-up of cardiac and renal function to improve patient outcomes. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Mosby | - |
dc.relation.isPartOf | JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Acute Kidney Injury / etiology* | - |
dc.subject.MESH | Acute Kidney Injury / pathology | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Cardiac Surgical Procedures / adverse effects* | - |
dc.subject.MESH | Disease Progression | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Heart Valves / surgery | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Postoperative Complications / etiology* | - |
dc.subject.MESH | Postoperative Complications / pathology | - |
dc.subject.MESH | Renal Insufficiency, Chronic / etiology | - |
dc.subject.MESH | Renal Insufficiency, Chronic / pathology | - |
dc.subject.MESH | Risk Factors | - |
dc.title | Chronic progression of cardiac surgery associated acute kidney injury: Intermediary role of acute kidney disease | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) | - |
dc.contributor.googleauthor | Jin Sun Cho | - |
dc.contributor.googleauthor | Jae-Kwang Shim | - |
dc.contributor.googleauthor | Sak Lee | - |
dc.contributor.googleauthor | Jong-Wook Song | - |
dc.contributor.googleauthor | Nakcheol Choi | - |
dc.contributor.googleauthor | Sugeun Lee | - |
dc.contributor.googleauthor | Young-Lan Kwak | - |
dc.identifier.doi | 10.1016/j.jtcvs.2019.10.101 | - |
dc.contributor.localId | A00172 | - |
dc.contributor.localId | A02060 | - |
dc.contributor.localId | A02205 | - |
dc.contributor.localId | A02807 | - |
dc.contributor.localId | A03914 | - |
dc.contributor.localId | A05521 | - |
dc.relation.journalcode | J01906 | - |
dc.identifier.eissn | 1097-685X | - |
dc.identifier.pmid | 31959433 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0022522319324857 | - |
dc.subject.keyword | acute kidney disease | - |
dc.subject.keyword | acute kidney injury | - |
dc.subject.keyword | chronic kidney disease | - |
dc.subject.keyword | heart failure | - |
dc.subject.keyword | valvular heart surgery | - |
dc.contributor.alternativeName | Kwak, Young Lan | - |
dc.contributor.affiliatedAuthor | 곽영란 | - |
dc.contributor.affiliatedAuthor | 송종욱 | - |
dc.contributor.affiliatedAuthor | 심재광 | - |
dc.contributor.affiliatedAuthor | 이삭 | - |
dc.contributor.affiliatedAuthor | 조진선 | - |
dc.contributor.affiliatedAuthor | 최낙철 | - |
dc.citation.volume | 161 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 681 | - |
dc.citation.endPage | 688.e3 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, Vol.161(2) : 681-688.e3, 2021-02 | - |
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