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Clinicopathologic Features of Submucosal Papillary Gastric Cancer Differ from Those of Other Differentiated-Type Histologies

DC FieldValueLanguage
dc.contributor.author김지현-
dc.contributor.author김현기-
dc.contributor.author노성훈-
dc.contributor.author이용찬-
dc.date.accessioned2021-04-29T16:56:03Z-
dc.date.available2021-04-29T16:56:03Z-
dc.date.issued2021-01-
dc.identifier.issn1976-2283-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/182096-
dc.description.abstractBackground/aims: Papillary gastric cancer (GC) is classified as differentiated adenocarcinoma, together with well-differentiated (WD) and moderately differentiated (MD) adenocarcinoma. This study evaluated the risk of lymph node metastasis (LNM) in submucosal (SM) invasive papillary GC compared with other differentiated early GC types. Methods: This retrospective study involved three tertiary hospitals and enrolled 1,798 lesions with differentiated SM invasive GC treated with curative gastrectomy between March 2001 and December 2012. All pathology slides were reviewed, and clinicopathologic findings associated with LNM, including tumor size, location, gross type, ulceration, depth and width of SM invasion, and lymphovascular invasion (LVI), were analyzed. Results: The proportion of SM papillary GC was 2.8% (n=51). SM papillary GC was associated with larger tumor size and deeper and wider SM invasion than other differentiated GC types. LNM was significantly higher in the papillary type than in the MD and WD types. LNM was found in 27.5% of SM papillary GC patients (WD: 9.0%, MD: 21.2%). LVI was the only significant risk factor for LNM in SM papillary GC. The depth or width of SM invasion was not associated with LNM in papillary GC. Lower third location or elevated gross appearance was significantly associated with LVI. Conclusions: SM papillary GC had the highest LNM rate, with features different from those of other differentiated SM invasive GCs. The treatment strategy for SM papillary GC should be carefully approached, especially for lesions located in the lower third or of the elevated gross type.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherEditorial Office of Gut and Liver-
dc.relation.isPartOfGUT AND LIVER-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleClinicopathologic Features of Submucosal Papillary Gastric Cancer Differ from Those of Other Differentiated-Type Histologies-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorSeung Yong Shin-
dc.contributor.googleauthorJie-Hyun Kim-
dc.contributor.googleauthorMyeong-Cherl Kook-
dc.contributor.googleauthorDo Youn Park-
dc.contributor.googleauthorKeun Won Ryu-
dc.contributor.googleauthorIl Ju Choi-
dc.contributor.googleauthorSung Hoon Noh-
dc.contributor.googleauthorHyunki Kim-
dc.contributor.googleauthorYong Chan Lee-
dc.identifier.doi10.5009/gnl19328-
dc.contributor.localIdA00996-
dc.contributor.localIdA01108-
dc.contributor.localIdA01281-
dc.contributor.localIdA02988-
dc.relation.journalcodeJ00954-
dc.identifier.eissn2005-1212-
dc.identifier.pmid32295332-
dc.subject.keywordAdenocarcinoma-
dc.subject.keywordLymphatic metastasis-
dc.subject.keywordRisk factors-
dc.subject.keywordStomach neoplasm-
dc.subject.keywordpapillary-
dc.contributor.alternativeNameKim, Jie-Hyun-
dc.contributor.affiliatedAuthor김지현-
dc.contributor.affiliatedAuthor김현기-
dc.contributor.affiliatedAuthor노성훈-
dc.contributor.affiliatedAuthor이용찬-
dc.citation.volume15-
dc.citation.number1-
dc.citation.startPage44-
dc.citation.endPage52-
dc.identifier.bibliographicCitationGUT AND LIVER, Vol.15(1) : 44-52, 2021-01-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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