Cited 12 times in
Infective endocarditis at a tertiary care hospital in South Korea
DC Field | Value | Language |
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dc.contributor.author | 구남수 | - |
dc.contributor.author | 김정호 | - |
dc.contributor.author | 염준섭 | - |
dc.contributor.author | 이삭 | - |
dc.contributor.author | 이승현 | - |
dc.contributor.author | 최준용 | - |
dc.date.accessioned | 2021-04-29T16:45:27Z | - |
dc.date.available | 2021-04-29T16:45:27Z | - |
dc.date.issued | 2021-01 | - |
dc.identifier.issn | 1355-6037 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/182003 | - |
dc.description.abstract | Objective: The treatment of infective endocarditis (IE) has become more complex with the current myriad healthcare-associated factors and the regional differences in causative organisms. We aimed to investigate the overall trends, microbiological features, and outcomes of IE in South Korea. Methods: A 12-year retrospective cohort study was performed. Poisson regression was used to estimate the time trends of IE incidence and mortality rate. Risk factors for in-hospital mortality were identified with multivariable logistic regression, and model comparison was performed to evaluate the predictive performance of notable risk factors. Kaplan-Meier survival analysis and Cox regression were performed to assess long-term prognosis. Results: We included 419 patients with IE, the incidence of which showed an increasing trend (relative risk 1.06, p=0.005), whereas mortality demonstrated a decreasing trend (incidence rate ratio 0.93, p=0.020). The in-hospital mortality rate was 14.6%. On multivariable logistic regression analysis, aortic valve endocarditis (OR 3.18, p=0.001), IE caused by Staphylococcus aureus (OR 2.32, p=0.026), neurological complications (OR 1.98, p=0.031), high Sequential Organ Failure Assessment score (OR 1.22, p=0.023) and high Charlson Comorbidity Index (OR 1.11, p=0.019) were predictors of in-hospital mortality. Surgical intervention for IE was a protective factor against in-hospital mortality (OR 0.25, p<0.001) and was associated with improved long-term prognosis compared with medical treatment only (p<0.001). Conclusions: The incidence of IE is increasing in South Korea. Although the mortality rate has slightly decreased, it remains high. Surgery has a protective effect with respect to both in-hospital mortality and long-term prognosis in patients with IE. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | BMJ Pub. Group. | - |
dc.relation.isPartOf | HEART | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Infective endocarditis at a tertiary care hospital in South Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jung Ho Kim | - |
dc.contributor.googleauthor | Hi Jae Lee | - |
dc.contributor.googleauthor | Nam Su Ku | - |
dc.contributor.googleauthor | Seung Hyun Lee | - |
dc.contributor.googleauthor | Sak Lee | - |
dc.contributor.googleauthor | Jun Yong Choi | - |
dc.contributor.googleauthor | Joon-Sup Yeom | - |
dc.identifier.doi | 10.1136/heartjnl-2020-317265 | - |
dc.contributor.localId | A00189 | - |
dc.contributor.localId | A00902 | - |
dc.contributor.localId | A02353 | - |
dc.contributor.localId | A02807 | - |
dc.contributor.localId | A02935 | - |
dc.contributor.localId | A04191 | - |
dc.relation.journalcode | J00976 | - |
dc.identifier.eissn | 1468-201X | - |
dc.identifier.pmid | 33033067 | - |
dc.subject.keyword | endocarditis | - |
dc.subject.keyword | valve disease surgery | - |
dc.contributor.alternativeName | Ku, Nam Su | - |
dc.contributor.affiliatedAuthor | 구남수 | - |
dc.contributor.affiliatedAuthor | 김정호 | - |
dc.contributor.affiliatedAuthor | 염준섭 | - |
dc.contributor.affiliatedAuthor | 이삭 | - |
dc.contributor.affiliatedAuthor | 이승현 | - |
dc.contributor.affiliatedAuthor | 최준용 | - |
dc.citation.volume | 107 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 135 | - |
dc.citation.endPage | 141 | - |
dc.identifier.bibliographicCitation | HEART, Vol.107(2) : 135-141, 2021-01 | - |
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