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Association between mortality risk and the number, location, and sequence of subsequent fractures in the elderly

DC FieldValueLanguage
dc.contributor.author권지원-
dc.contributor.author양재호-
dc.contributor.author이병호-
dc.contributor.author석경수-
dc.contributor.author문성환-
dc.contributor.author김학선-
dc.contributor.author이환모-
dc.date.accessioned2021-04-01T07:59:04Z-
dc.date.available2021-04-01T07:59:04Z-
dc.date.issued2021-02-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/181894-
dc.description.abstractThe mortality risk showed a positive correlation as the number of subsequent fractures increased. Hip fracture showed the greatest association with mortality risk, followed by vertebral fracture. For the combination of hip and vertebral fracture, a hip fracture after a vertebral fracture showed the highest mortality risk. Introduction: It is unclear whether subsequent fractures or a certain location and sequence of subsequent fractures are associated with mortality risk in the elderly. We aimed to investigate the relationship between subsequent fractures and mortality risk. Methods: Using the Korean National Health Insurance Research Database, we analyzed the cohort data of 24,756 patients aged > 60 years who sustained fractures between 2002 and 2013. Cox regression was used to assess the mortality risk associated with the number, locations, and sequences of subsequent fractures. Results: Mortality hazard ratios (HRs) for women and men were shown to be associated with the number of subsequent fractures (one, 1.63 (95% confidence interval [CI], 1.48-1.80) and 1.42 (95% CI, 1.28-1.58); two, 1.75 (95% CI, 1.47-2.08) and 2.03 (95% CI, 1.69-2.43); three or more, 2.46(95% CI, 1.92-3.15) and 1.92 (95% CI, 1.34-2.74), respectively). For women, the mortality risk was high when hip (HR, 2.49; 95% CI, 1.80-3.44) or vertebral (HR, 1.40; 95% CI, 1.03-1.90) fracture occurred as a second fracture. Compared with a single hip fracture, there was a high mortality risk in the group with hip fracture after the first vertebral fracture (HR, 2.90; 95% CI, 1.86-4.54), followed by vertebral fracture after the first hip fracture (HR, 1.90; 95% CI, 1.12-3.22). Conclusion: The mortality risk showed a positive correlation as the number of subsequent fractures increased. Hip fracture showed the greatest association with mortality risk, followed by vertebral fracture. For the combination of hip and vertebral fracture, a hip fracture after a vertebral fracture showed the highest mortality risk.-
dc.description.statementOfResponsibilityrestriction-
dc.relation.isPartOfOSTEOPOROSIS INTERNATIONAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAged-
dc.subject.MESHCohort Studies-
dc.subject.MESHFemale-
dc.subject.MESHHip Fractures*-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHRisk Factors-
dc.subject.MESHSpinal Fractures*-
dc.subject.MESHSpine-
dc.titleAssociation between mortality risk and the number, location, and sequence of subsequent fractures in the elderly-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Orthopedic Surgery (정형외과학교실)-
dc.contributor.googleauthorS-B Lee-
dc.contributor.googleauthorY Park-
dc.contributor.googleauthorD-W Kim-
dc.contributor.googleauthorJ-W Kwon-
dc.contributor.googleauthorJ-W Ha-
dc.contributor.googleauthorJ-H Yang-
dc.contributor.googleauthorB H Lee-
dc.contributor.googleauthorK-S Suk-
dc.contributor.googleauthorS-H Moon-
dc.contributor.googleauthorH-S Kim-
dc.contributor.googleauthorH-M Lee-
dc.identifier.doi10.1007/s00198-020-05602-x-
dc.contributor.localIdA06027-
dc.contributor.localIdA02317-
dc.contributor.localIdA02801-
dc.contributor.localIdA01926-
dc.contributor.localIdA01365-
dc.contributor.localIdA01093-
dc.contributor.localIdA03333-
dc.identifier.pmid32820370-
dc.identifier.urlhttps://link.springer.com/article/10.1007/s00198-020-05602-x-
dc.subject.keywordHip fracture-
dc.subject.keywordMortality risk-
dc.subject.keywordOsteoporosis-
dc.subject.keywordSubsequent fracture-
dc.subject.keywordVertebral fracture-
dc.contributor.alternativeNameKwon, Ji-Won-
dc.contributor.affiliatedAuthor권지원-
dc.contributor.affiliatedAuthor양재호-
dc.contributor.affiliatedAuthor이병호-
dc.contributor.affiliatedAuthor석경수-
dc.contributor.affiliatedAuthor문성환-
dc.contributor.affiliatedAuthor김학선-
dc.contributor.affiliatedAuthor이환모-
dc.citation.volume32-
dc.citation.number2-
dc.citation.startPage233-
dc.citation.endPage241-
dc.identifier.bibliographicCitationOSTEOPOROSIS INTERNATIONAL, Vol.32(2) : 233-241, 2021-02-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers

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