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Dysphagia in Wilson’s Disease: A Case Report of One-Year Follow-Up

DC FieldValueLanguage
dc.contributor.author박진영-
dc.contributor.author박윤길-
dc.contributor.author박중현-
dc.date.accessioned2021-02-17T06:42:01Z-
dc.date.available2021-02-17T06:42:01Z-
dc.date.issued2021-01-
dc.identifier.issn2233-5978-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/181686-
dc.description.abstractWilson’s disease (WD) is a genetic disease caused by an ATP7B gene mutation. Although dysphagia is known as a neurological manifestation of WD, clinical case reports with post-treatment long-term follow-up are scarce. A 17- year-old male was admitted to hospital complaining of general weakness and swallowing difficulty. He was diagnosed with WD by genetic confirmation. Assessment of the videofluoroscopic swallowing study (VFSS) determined an initial videofluoroscopic dysphagia scale (VDS) score of 48. After 11 months treatment with D-penicillamine and neuromuscular electrical stimulation therapy (NMES) with oromotor exercises, the VDS score improved to 23, especially in the following areas: mastication, apraxia, premature bolus loss, triggering of pharyngeal swallow, and laryngeal elevation. Dysphagia is an early neurological symptom of WD, and is reversible when properly treated with early diagnosis. Thus, since WD is treatable, patients presenting with dysphagia should be indicative of high probability of the disease, and evaluated at the earliest. NMES treatment in combination with D-penicillamine helps to improve the deglutition function in both oral and pharyngeal phases. To investigate the characteristics of dysphagia and the specific clinical efficacy of NMES in WD, further studies with larger number of patients are required.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean-
dc.publisher대한연하장애학회-
dc.relation.isPartOfJournal of the Korean Dysphagia Society (대한연하장애학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleDysphagia in Wilson’s Disease: A Case Report of One-Year Follow-Up-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Rehabilitation Medicine (재활의학교실)-
dc.contributor.googleauthorDoyoung Kim-
dc.contributor.googleauthorYoon Ghil Park-
dc.contributor.googleauthorJung Hyun Park-
dc.contributor.googleauthorJinyoung Park-
dc.identifier.doi10.34160/jkds.2021.11.1.012-
dc.contributor.localIdA04941-
dc.contributor.localIdA01596-
dc.contributor.localIdA01682-
dc.relation.journalcodeJ01823-
dc.subject.keywordWilson’s disease-
dc.subject.keywordDeglutition disorders-
dc.subject.keywordElectrical stimulation-
dc.contributor.alternativeNamePark, Jinyoung-
dc.contributor.affiliatedAuthor박진영-
dc.contributor.affiliatedAuthor박윤길-
dc.contributor.affiliatedAuthor박중현-
dc.citation.volume11-
dc.citation.number1-
dc.citation.startPage82-
dc.citation.endPage86-
dc.identifier.bibliographicCitationJournal of the Korean Dysphagia Society (대한연하장애학회지), Vol.11(1) : 82-86, 2021-01-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers

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