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Age- and sex-related characteristics of the increasing trend of nontuberculous mycobacteria pulmonary disease in a tertiary hospital in South Korea from 2006 to 2016

DC Field Value Language
dc.contributor.author박영목-
dc.contributor.author박무석-
dc.contributor.author장준-
dc.contributor.author강영애-
dc.date.accessioned2021-02-03T05:56:27Z-
dc.date.available2021-02-03T05:56:27Z-
dc.date.issued2020-11-
dc.identifier.issn1226-3303-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/181603-
dc.description.abstractBackground/aims: The incidence rate of nontuberculous mycobacterial pulmonary disease (NTM-PD) is increasing worldwide. However, data regarding the age- and sex-specific epidemiology of NTM-PD are limited. This study aimed to investigate the long-term epidemiologic trends of NTM-PD within the recent 11- year period in a tertiary referral hospital in Korea. Methods: We retrospectively reviewed the medical records of the patients diagnosed with NTM-PD between January 2006 and December 2016 at Severance Hospital, South Korea. Results: There were 1,017 incident cases with NTM-PD during the study period. The mean age was 62.7 years, and 41.2% were men. Women were younger than men (59.9 years vs. 66.7 years, p < 0.001) and a higher proportion of women had bronchiectasis (88.6% vs. 77.1%, p < 0.001). The incidence rates of NTM-PD annually increased by 14% (95% confidence interval, 10% to 19%) from 1.2 in 2006 to 4.8 in 2016 (per 100,000 patients-year). The peak incidence rate was in the 50s for women and in the 70s for men, except for those aged ≥ 80 years. Mycobacterium avium complex was the most common causative species of NTM-PD (63.6%). Conclusion: The incidence rate of NTM-PD in a tertiary referral hospital in South Korea continued to increase from 2006 to 2016. Furthermore, there were age- and sex-related differences in the clinical characteristics, which might contribute to understanding the nature of the disease and inherited and acquired host factors.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherKorean Association of Internal Medicine-
dc.relation.isPartOfKOREAN JOURNAL OF INTERNAL MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleAge- and sex-related characteristics of the increasing trend of nontuberculous mycobacteria pulmonary disease in a tertiary hospital in South Korea from 2006 to 2016-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorYoungmok Park-
dc.contributor.googleauthorChi Young Kim-
dc.contributor.googleauthorMoo Suk Park-
dc.contributor.googleauthorYoung Sam Kim-
dc.contributor.googleauthorJoon Chang-
dc.contributor.googleauthorYoung Ae Kang-
dc.identifier.doi10.3904/kjim.2019.395-
dc.contributor.localIdA05828-
dc.contributor.localIdA01457-
dc.contributor.localIdA03472-
dc.contributor.localIdA00057-
dc.relation.journalcodeJ02883-
dc.identifier.eissn2005-6648-
dc.identifier.pmid32550717-
dc.subject.keywordLung diseases-
dc.subject.keywordNontuberculous mycobacteria-
dc.subject.keywordNontuberculous mycobacterium infection-
dc.contributor.alternativeNamePark, Youngmok-
dc.contributor.affiliatedAuthor박영목-
dc.contributor.affiliatedAuthor박무석-
dc.contributor.affiliatedAuthor장준-
dc.contributor.affiliatedAuthor강영애-
dc.citation.volume35-
dc.citation.number6-
dc.citation.startPage1424-
dc.citation.endPage1431-
dc.identifier.bibliographicCitationKOREAN JOURNAL OF INTERNAL MEDICINE, Vol.35(6) : 1424-1431, 2020-11-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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