Cited 1 times in
소아 Clostridioides difficile 감염의 발생률 및 임상양상
DC Field | Value | Language |
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dc.contributor.author | 강지만 | - |
dc.contributor.author | 안종균 | - |
dc.date.accessioned | 2021-01-19T08:12:06Z | - |
dc.date.available | 2021-01-19T08:12:06Z | - |
dc.date.issued | 2020-12 | - |
dc.identifier.issn | 2384-1079 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/181508 | - |
dc.description.abstract | Purpose: We evaluated the incidence and characteristics of Clostridioides difficile infection (CDI) in Korean children. Methods: Medical records of patients aged 2–18 years and diagnosed with CDI at a tertiary hospital between 2009 and 2018 were analyzed. The patients were classified into three CDI groups: community-acquired (CA), community onset-health care facility-associated (CO-HCFA), and healthcare facility onset (HO). Results: The incidence of CDI increased from 1.00 to 10.01 cases per 10,000 admissions from 2009 to 2018 (P<0.001). As compared to the CA group, the HO group had a higher frequency of operation and malignancy as predisposing factors (40.4% vs. 0.0%, P=0.001; and 27.7% vs. 0.0%, P=0.027, respectively), frequency and number of previous antibiotic use (97.9% vs. 31.3%, P<0.001; and 2 vs. 0, P<0.001, respectively), and median postdiagnosis hospital stay (13 vs. 5 days, P=0.008). The CO-HCFA group had a lower median age and higher frequency of malignancy than the CA group (5 vs. 13 years, P=0.012; and 30.8% vs. 0.0%, P=0.030, respectively). As compared to the HO group, the CA group had a higher frequency of abdominal pain and hematochezia (56.3% vs. 10.6%, P=0.001; and 50.0% vs. 10.6%, P=0.002, respectively), inflammatory bowel disease (68.8% vs. 2.1%, P=0.001), and intravenous metronidazole treatment (37.5% vs. 2.1%, P=0.001). Conclusions: With the increasing incidence of pediatric CDI, awareness regarding its epidemiology and clinical characteristics is important to manage nosocomial infections. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | Korean Society of Pediatric Infectious Diseases | - |
dc.relation.isPartOf | Pediatric Infection & Vaccine | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 소아 Clostridioides difficile 감염의 발생률 및 임상양상 | - |
dc.title.alternative | Incidence and Characteristics of Clostridioides difficile Infection in Children | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | ;Dept. of Pediatrics (소아과학교실) | - |
dc.contributor.googleauthor | 정희라 | - |
dc.contributor.googleauthor | 강지만 | - |
dc.contributor.googleauthor | 안종균 | - |
dc.identifier.doi | 10.14776/piv.2020.27.e24 | - |
dc.contributor.localId | A05720 | - |
dc.contributor.localId | A02261 | - |
dc.relation.journalcode | J02486 | - |
dc.identifier.eissn | 2384-1087 | - |
dc.subject.keyword | Clostridioides difficile | - |
dc.subject.keyword | Child | - |
dc.subject.keyword | Epidemiology | - |
dc.contributor.alternativeName | Kang, Ji-Man | - |
dc.contributor.affiliatedAuthor | 강지만 | - |
dc.contributor.affiliatedAuthor | 안종균 | - |
dc.citation.volume | 27 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 158 | - |
dc.citation.endPage | 170 | - |
dc.identifier.bibliographicCitation | Pediatric Infection & Vaccine, Vol.27(3) : 158-170, 2020-12 | - |
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