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소아 Clostridioides difficile 감염의 발생률 및 임상양상

DC FieldValueLanguage
dc.contributor.author강지만-
dc.contributor.author안종균-
dc.date.accessioned2021-01-19T08:12:06Z-
dc.date.available2021-01-19T08:12:06Z-
dc.date.issued2020-12-
dc.identifier.issn2384-1079-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/181508-
dc.description.abstractPurpose: We evaluated the incidence and characteristics of Clostridioides difficile infection (CDI) in Korean children. Methods: Medical records of patients aged 2–18 years and diagnosed with CDI at a tertiary hospital between 2009 and 2018 were analyzed. The patients were classified into three CDI groups: community-acquired (CA), community onset-health care facility-associated (CO-HCFA), and healthcare facility onset (HO). Results: The incidence of CDI increased from 1.00 to 10.01 cases per 10,000 admissions from 2009 to 2018 (P<0.001). As compared to the CA group, the HO group had a higher frequency of operation and malignancy as predisposing factors (40.4% vs. 0.0%, P=0.001; and 27.7% vs. 0.0%, P=0.027, respectively), frequency and number of previous antibiotic use (97.9% vs. 31.3%, P<0.001; and 2 vs. 0, P<0.001, respectively), and median postdiagnosis hospital stay (13 vs. 5 days, P=0.008). The CO-HCFA group had a lower median age and higher frequency of malignancy than the CA group (5 vs. 13 years, P=0.012; and 30.8% vs. 0.0%, P=0.030, respectively). As compared to the HO group, the CA group had a higher frequency of abdominal pain and hematochezia (56.3% vs. 10.6%, P=0.001; and 50.0% vs. 10.6%, P=0.002, respectively), inflammatory bowel disease (68.8% vs. 2.1%, P=0.001), and intravenous metronidazole treatment (37.5% vs. 2.1%, P=0.001). Conclusions: With the increasing incidence of pediatric CDI, awareness regarding its epidemiology and clinical characteristics is important to manage nosocomial infections.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean-
dc.publisherKorean Society of Pediatric Infectious Diseases-
dc.relation.isPartOfPediatric Infection & Vaccine-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.title소아 Clostridioides difficile 감염의 발생률 및 임상양상-
dc.title.alternativeIncidence and Characteristics of Clostridioides difficile Infection in Children-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.department;Dept. of Pediatrics (소아과학교실)-
dc.contributor.googleauthor정희라-
dc.contributor.googleauthor강지만-
dc.contributor.googleauthor안종균-
dc.identifier.doi10.14776/piv.2020.27.e24-
dc.contributor.localIdA05720-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.relation.journalcodeJ02486-
dc.identifier.eissn2384-1087-
dc.subject.keywordClostridioides difficile-
dc.subject.keywordChild-
dc.subject.keywordEpidemiology-
dc.contributor.alternativeNameKang, Ji-Man-
dc.contributor.affiliatedAuthor강지만-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.citation.volume27-
dc.citation.number3-
dc.citation.startPage158-
dc.citation.endPage170-
dc.identifier.bibliographicCitationPediatric Infection & Vaccine, Vol.27(3) : 158-170, 2020-12-
Appears in Collections:
1. College of Medicine (의과대학) > Others (기타) > 1. Journal Papers

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