Cited 21 times in
Reirradiation with intensity-modulated radiation therapy for recurrent or secondary head and neck cancer: Meta-analysis and systematic review
DC Field | Value | Language |
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dc.contributor.author | 금웅섭 | - |
dc.date.accessioned | 2021-01-19T08:09:57Z | - |
dc.date.available | 2021-01-19T08:09:57Z | - |
dc.date.issued | 2020-09 | - |
dc.identifier.issn | 1043-3074 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/181489 | - |
dc.description.abstract | Background: To summarize outcomes of reirradiation with intensity-modulated radiotherapy (IMRT) for recurrent or secondary head and neck cancer (HNC). Methods: Primary endpoints were 2-year local control (LC) and overall survival (OS). Studies involving only recurrent nasopharyngeal patients with cancer were excluded. Results: A total of 17 studies involving 1635 patients were included. Fourteen (82%) of those were retrospective, and 15 (88%) were from single institution. Reirradiation with IMRT produced pooled 2-year LC and OS rates of 52% (95% confidence interval [CI], 46%-57%) and 46% (95% CI, 41%-50%), respectively. In subgroup analyses, the rate of salvage surgery (<42% vs ≥42%) influenced the pooled 2-year LC rate (45.9% vs 58.5%, P = .011). The pooled rates of late grade ≥ 3 and grade 5 toxicities were 26% (95% CI, 20%-32%) and 3.1% (95% CI, 2%-5%), respectively. Conclusions: Reirradiation with IMRT was an effective modality compared to historical outcomes in the pre-IMRT era. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | John Wiley And Sons | - |
dc.relation.isPartOf | HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Reirradiation with intensity-modulated radiation therapy for recurrent or secondary head and neck cancer: Meta-analysis and systematic review | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiation Oncology (방사선종양학교실) | - |
dc.contributor.googleauthor | Jeongshim Lee | - |
dc.contributor.googleauthor | In-Soo Shin | - |
dc.contributor.googleauthor | Woo Chul Kim | - |
dc.contributor.googleauthor | Won Sup Yoon | - |
dc.contributor.googleauthor | Woong Sub Koom | - |
dc.contributor.googleauthor | Chai Hong Rim | - |
dc.identifier.doi | 10.1002/hed.26264 | - |
dc.contributor.localId | A00273 | - |
dc.relation.journalcode | J00963 | - |
dc.identifier.eissn | 1097-0347 | - |
dc.identifier.pmid | 32437021 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1002/hed.26264 | - |
dc.subject.keyword | head and neck cancer | - |
dc.subject.keyword | intensity-modulated radiotherapy | - |
dc.subject.keyword | meta-analysis | - |
dc.subject.keyword | recurrence | - |
dc.subject.keyword | reirradiation | - |
dc.contributor.alternativeName | Koom, Woong Sub | - |
dc.contributor.affiliatedAuthor | 금웅섭 | - |
dc.citation.volume | 42 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 2473 | - |
dc.citation.endPage | 2485 | - |
dc.identifier.bibliographicCitation | HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, Vol.42(9) : 2473-2485, 2020-09 | - |
dc.identifier.rimsid | 67348 | - |
dc.type.rims | ART | - |
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