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Hybrid Machine Learning Scheme for Classification of BECTS and TLE Patients Using EEG Brain Signals

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dc.contributor.author김세희-
dc.date.accessioned2021-01-19T08:05:41Z-
dc.date.available2021-01-19T08:05:41Z-
dc.date.issued2020-11-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/181462-
dc.description.abstractApproximately 50 million people have epilepsyworldwide. Prognosis may vary among patients depending on their seizure semiology, age of onset, seizure onset location, and features of electroencephalogram (EEG). Several researchers have focused on EEG patterns and demonstrated that EEG patterns of individuals with epilepsy can be used to predict prognosis and treatment responses. However, accurate EEG analysis requires an experienced epileptologist with several years of training, who are often unavailable in small or medium sized hospitals. In this paper, a novel machine learning (ML) model that accurately distinguishes Benign Epilepsy with Centrotemporal Spikes (BECTS) from Temporal Lobe Epilepsy (TLE) is proposed. BECTS and TLE show different seizure types and age of onset, but differential diagnosis can be challenging due to the similar location and patterns of the EEG spikes. The proposed hybrid machine learning (HML) model processes the diagnosis in the order of (1) creating feature matrices using statistical indexes after signal decomposition, (2) processing feature selection using Support Vector Machine (SVM) technology, and (3) classifying the results through ensemble learning based on decision trees. Simulation was performed using real patient data of 112 BECTS and 112 TLE EEG signals, where training was performed using 80% of the data and 20% of the data was used in the performance analysis comparison with the actual labeled data based on the diagnosis of medical doctors. The performance of the hybrid classi cation model is compared with other representative ML algorithms, which include logistic regression, KNN, SVM, and ensemble learning based decision tree. The model proposed in this paper shows an accuracy performance exceeding 99%, which is higher than the performance obtainable from the other ML classi cation models. The purpose of this study is to introduce a novel EEG diagnostic system that shows maximum ef ciency to support clinical real-time diagnosis that can accurately distinguish epilepsy types. Future research will focus on expanding this ML model to categorize other types of epilepsies beyond BECTS and TLE and implement the HML diagnostic blockchain database into the hospital system.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherInstitute of Electrical and Electronics Engineers-
dc.relation.isPartOfIEEE ACCESS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleHybrid Machine Learning Scheme for Classification of BECTS and TLE Patients Using EEG Brain Signals-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.department;Dept. of Pediatrics (소아과학교실)-
dc.contributor.googleauthorWonsik Yang-
dc.contributor.googleauthorMinsoo Joo-
dc.contributor.googleauthorYujaung Kim-
dc.contributor.googleauthorSe Hee Kim-
dc.contributor.googleauthorJong-Moon Chung-
dc.identifier.doi10.1109/ACCESS.2020.3038948-
dc.contributor.localIdA00611-
dc.relation.journalcodeJ03454-
dc.identifier.eissn2169-3536-
dc.subject.keywordElectroencephalogram (EEG)-
dc.subject.keywordbrain signal-
dc.subject.keywordepilepsy-
dc.subject.keywordhybrid machine learning-
dc.subject.keywordempirical mode decomposition (EMD)-
dc.contributor.alternativeNameKim, Se Hee-
dc.contributor.affiliatedAuthor김세희-
dc.citation.volume8-
dc.citation.startPage218924-
dc.citation.endPage218935-
dc.identifier.bibliographicCitationIEEE ACCESS, Vol.8 : 218924-218935, 2020-11-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

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