Cited 14 times in
Effect of sex hormones on coronavirus disease 2019: an analysis of 5,061 laboratory-confirmed cases in South Korea
DC Field | Value | Language |
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dc.contributor.author | 김용찬 | - |
dc.contributor.author | 박윤수 | - |
dc.contributor.author | 송영구 | - |
dc.contributor.author | 이재훈 | - |
dc.contributor.author | 조시현 | - |
dc.date.accessioned | 2021-01-19T08:04:37Z | - |
dc.date.available | 2021-01-19T08:04:37Z | - |
dc.date.issued | 2020-12 | - |
dc.identifier.issn | 1072-3714 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/181455 | - |
dc.description.abstract | Objective: To evaluate the effect of female sex hormones on the clinical outcomes of coronavirus disease 2019 patients using national claims data. Methods: This retrospective cohort study used the Health Insurance Review and Assessment data of 5,061 adult patients with laboratory-confirmed coronavirus disease 2019 in South Korea from January 20 to April 8, 2020. To evaluate the effect of hormone therapy on clinical outcomes among women, subgroup analyses using age-matched case-control data were performed. Results: Coronavirus disease 2019 was most prevalent in women in the 20-39 years age group (1,250 [44.14%]). Men were more likely to receive oxygen therapy (144 [6.46%] vs 131 [4.63%], P = 0.004), be admitted to the intensive care unit (60 [2.69%] vs 53 [1.87%], P = 0.049), and have a longer length of stay after admission to the intensive care unit (19.70 ± 11.80 vs 14.75 ± 9.23, P = 0.016). However, there was no significant difference in the mortality rate (men vs women: 42 [1.88%] vs 42 [1.48%], P = 0.267). In the multivariable Cox analysis, older age and underlying comorbidities, but not sex, were independent risk factors for mortality. Hormone therapy was not significantly associated with clinical outcomes. Conclusions: This study, using nationwide data, suggests that female sex hormones are not associated with the morbidity and clinical outcomes of coronavirus disease 2019 in South Korea. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Lippincott-Raven Publishers | - |
dc.relation.isPartOf | MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | COVID-19 / epidemiology* | - |
dc.subject.MESH | COVID-19 / metabolism* | - |
dc.subject.MESH | COVID-19 Testing / statistics & numerical data* | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Gonadal Steroid Hormones / metabolism* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | SARS-CoV-2 / metabolism | - |
dc.subject.MESH | Young Adult | - |
dc.title | Effect of sex hormones on coronavirus disease 2019: an analysis of 5,061 laboratory-confirmed cases in South Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jae Hoon Lee | - |
dc.contributor.googleauthor | Yong Chan Kim | - |
dc.contributor.googleauthor | Si Hyun Cho | - |
dc.contributor.googleauthor | Jinae Lee | - |
dc.contributor.googleauthor | Seng Chan You | - |
dc.contributor.googleauthor | Young Goo Song | - |
dc.contributor.googleauthor | Young Bin Won | - |
dc.contributor.googleauthor | Young Sik Choi | - |
dc.contributor.googleauthor | Yun Soo Park | - |
dc.identifier.doi | 10.1097/GME.0000000000001657 | - |
dc.contributor.localId | A00752 | - |
dc.contributor.localId | A01598 | - |
dc.contributor.localId | A02037 | - |
dc.contributor.localId | A04636 | - |
dc.contributor.localId | A03846 | - |
dc.relation.journalcode | J02219 | - |
dc.identifier.eissn | 1530-0374 | - |
dc.identifier.pmid | 33003134 | - |
dc.contributor.alternativeName | Kim, Yong Chan | - |
dc.contributor.affiliatedAuthor | 김용찬 | - |
dc.contributor.affiliatedAuthor | 박윤수 | - |
dc.contributor.affiliatedAuthor | 송영구 | - |
dc.contributor.affiliatedAuthor | 이재훈 | - |
dc.contributor.affiliatedAuthor | 조시현 | - |
dc.citation.volume | 27 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1376 | - |
dc.citation.endPage | 1381 | - |
dc.identifier.bibliographicCitation | MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, Vol.27(12) : 1376-1381, 2020-12 | - |
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