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Oral health and changes in lipid profile: A nationwide cohort study

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dc.contributor.author김진권-
dc.date.accessioned2021-01-19T07:53:03Z-
dc.date.available2021-01-19T07:53:03Z-
dc.date.issued2020-12-
dc.identifier.issn0303-6979-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/181366-
dc.description.abstractAim: We aimed to investigate the association of periodontitis and oral hygiene indicators with changes in blood lipid parameters in a nationwide, population-based cohort in a longitudinal setting. Materials and methods: We included nationwide health screening program participants who underwent oral health examination in 2009-2010 and follow-up examinations for lipid profile without exposure to lipid-lowering agents. Results: During the 5.19-year median follow-up, 65,078 individuals (mean age at baseline examination: 55.41 ± 7.30 years) underwent 286,218 health examinations. The prevalence of periodontitis was 39%. In the multivariate mixed model analysis, periodontitis and tooth loss were associated with decreased high-density lipoprotein cholesterol levels (β = -0.0066 mmol/L, standard error = 0.0026, p = .013) and increased triglyceride levels (β=0.0307, mmol/L, standard error = 0.0049, p < .001), respectively. Compared with tooth brushing ≤1 time/day, tooth brushing ≥3 times/day was associated with increased high-density lipoprotein cholesterol levels (β = 0.0176 mmol/L, standard error = 0.0052, p = .006) and decreased triglyceride levels (β = -0.0285 mmol/L, standard error = 0.0090, p = .001). Conclusions: Periodontitis and tooth loss may be attenuating factors for blood high-density lipoprotein cholesterol and triglyceride levels, respectively. Frequent tooth brushing may improve dyslipidaemia, particularly blood high-density lipoprotein cholesterol and triglyceride levels. Oral hygiene improvement may reduce the risk of dyslipidaemia.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherWiley-Blackwell-
dc.relation.isPartOfJOURNAL OF CLINICAL PERIODONTOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleOral health and changes in lipid profile: A nationwide cohort study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurology (신경과학교실)-
dc.contributor.googleauthorTae-Jin Song-
dc.contributor.googleauthorJin-Woo Kim-
dc.contributor.googleauthorJinkwon Kim-
dc.identifier.doi10.1111/jcpe.13373-
dc.contributor.localIdA01012-
dc.relation.journalcodeJ01337-
dc.identifier.eissn1600-051X-
dc.identifier.pmid32996160-
dc.identifier.urlhttps://onlinelibrary.wiley.com/doi/10.1111/jcpe.13373-
dc.subject.keyworddyslipidaemia-
dc.subject.keywordoral hygiene-
dc.subject.keywordperiodontal diseases-
dc.subject.keywordtoothbrushing-
dc.subject.keywordtriglyceride-
dc.contributor.alternativeNameKim, Jin Kwon-
dc.contributor.affiliatedAuthor김진권-
dc.citation.volume47-
dc.citation.number12-
dc.citation.startPage1437-
dc.citation.endPage1445-
dc.identifier.bibliographicCitationJOURNAL OF CLINICAL PERIODONTOLOGY, Vol.47(12) : 1437-1445, 2020-12-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers

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