Cited 4 times in
Ambient carbon monoxide exposure and elevated risk of mortality in the glioblastoma patients: A double-cohort retrospective observational study
DC Field | Value | Language |
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dc.contributor.author | 강석구 | - |
dc.contributor.author | 김세훈 | - |
dc.contributor.author | 김의현 | - |
dc.contributor.author | 노주환 | - |
dc.contributor.author | 문주형 | - |
dc.contributor.author | 박상욱 | - |
dc.contributor.author | 손혜영 | - |
dc.contributor.author | 윤선진 | - |
dc.contributor.author | 장종희 | - |
dc.contributor.author | 허용민 | - |
dc.date.accessioned | 2021-01-19T07:50:22Z | - |
dc.date.available | 2021-01-19T07:50:22Z | - |
dc.date.issued | 2020-12 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/181344 | - |
dc.description.abstract | An increasing number of studies indicate air pollutants infiltrate into the brain. We aimed to find the association of cumulative air pollution exposure in the main body of primary brain tumor: glioblastoma (GBM). In this double-cohort, retrospective analysis study with a protocol, we compared the health effect of air pollution on the GBM patients from the SEER (Surveillance, Epidemiology, and End Results Program) in 27 U.S. counties from 10 states and GBM patients of Severance cohort of Korea. From 2000 to 2015, 10621 GBM patients of the SEER were individually evaluated for the cumulative average exposure for each pollutant, and 9444 (88.9%) mortality events were reported. From 2011 to 2018, 398 GBM patients of the Severance with the same protocol showed 259 (65.1%) mortality events. The multi-pollutant models show that the association level of risk with CO is increased in the SEER (HR 1.252; 95% CI 1.141-1.373) with an increasing linear trend of relative death rate in the spline curve. The Severance GBM data showed such a statistically significant result of the health impact of CO on GBM patients. The overall survival gain of the less exposure group against CO was 2 and 3 months in the two cohorts. Perioperative exposure to CO may increase the risk of shorter survival of GBM patients of the SEER and the Severance cohort. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | John Wiley & Sons Ltd. | - |
dc.relation.isPartOf | CANCER MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Ambient carbon monoxide exposure and elevated risk of mortality in the glioblastoma patients: A double-cohort retrospective observational study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurosurgery (신경외과학교실) | - |
dc.contributor.googleauthor | Seon-Jin Yoon | - |
dc.contributor.googleauthor | Juhwan Noh | - |
dc.contributor.googleauthor | Hye Young Son | - |
dc.contributor.googleauthor | Ju Hyung Moon | - |
dc.contributor.googleauthor | Eui-Hyun Kim | - |
dc.contributor.googleauthor | Sahng Wook Park | - |
dc.contributor.googleauthor | Se Hoon Kim | - |
dc.contributor.googleauthor | Jong Hee Chang | - |
dc.contributor.googleauthor | Yong-Min Huh | - |
dc.contributor.googleauthor | Seok-Gu Kang | - |
dc.identifier.doi | 10.1002/cam4.3572 | - |
dc.contributor.localId | A00036 | - |
dc.contributor.localId | A00610 | - |
dc.contributor.localId | A00837 | - |
dc.contributor.localId | A04866 | - |
dc.contributor.localId | A01383 | - |
dc.contributor.localId | A01487 | - |
dc.contributor.localId | A04589 | - |
dc.contributor.localId | A05256 | - |
dc.contributor.localId | A03470 | - |
dc.contributor.localId | A04359 | - |
dc.relation.journalcode | J00449 | - |
dc.identifier.eissn | 2045-7634 | - |
dc.identifier.pmid | 33161654 | - |
dc.subject.keyword | ambient air pollution | - |
dc.subject.keyword | carbon monoxide | - |
dc.subject.keyword | glioblastoma | - |
dc.subject.keyword | mortality | - |
dc.contributor.alternativeName | Kang, Seok Gu | - |
dc.contributor.affiliatedAuthor | 강석구 | - |
dc.contributor.affiliatedAuthor | 김세훈 | - |
dc.contributor.affiliatedAuthor | 김의현 | - |
dc.contributor.affiliatedAuthor | 노주환 | - |
dc.contributor.affiliatedAuthor | 문주형 | - |
dc.contributor.affiliatedAuthor | 박상욱 | - |
dc.contributor.affiliatedAuthor | 손혜영 | - |
dc.contributor.affiliatedAuthor | 윤선진 | - |
dc.contributor.affiliatedAuthor | 장종희 | - |
dc.contributor.affiliatedAuthor | 허용민 | - |
dc.citation.volume | 9 | - |
dc.citation.number | 23 | - |
dc.citation.startPage | 9018 | - |
dc.citation.endPage | 9026 | - |
dc.identifier.bibliographicCitation | CANCER MEDICINE, Vol.9(23) : 9018-9026, 2020-12 | - |
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