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Association of Reproductive Lifespan Duration and Chronic Kidney Disease in Postmenopausal Women

DC FieldValueLanguage
dc.contributor.author강신욱-
dc.contributor.author강신찬-
dc.contributor.author남기헌-
dc.contributor.author박정탁-
dc.contributor.author유태현-
dc.contributor.author윤해룡-
dc.contributor.author이상미-
dc.contributor.author지종현-
dc.contributor.author한승혁-
dc.date.accessioned2021-01-19T07:49:11Z-
dc.date.available2021-01-19T07:49:11Z-
dc.date.issued2020-12-
dc.identifier.issn0025-6196-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/181339-
dc.description.abstractObjective: To investigate the relationship between endogenous estrogen exposure and renal function, the association of female reproductive life span duration (RLD) and chronic kidney disease (CKD) was analyzed in postmenopausal women. Patients and methods: Data were retrieved from the Korean Genome and Epidemiology Study, which was constructed from May 1, 2001, through December 25, 2017. A total of 50,338 and 3155 postmenopausal women were each included in the cross-sectional and longitudinal analyses. The RLD was determined by subtracting the age at menarche from the age at menopause. Participants were grouped into RLD quartiles. Participants with estimated glomerular filtration rates less than 60 mL/min/1.73 m2 were regarded to have CKD. Results: In the cross-sectional analysis, mean ± SD age and estimated glomerular filtration rate were 56.3±4.9 years and 93.1±13.6 mL/min/1.73 m2, respectively. Mean ± SD RLD was 34.2±4.0 years. A total of 765 of 50,338 (1.52%) women were found to have CKD. Logistic regression analysis revealed that the odds ratio for CKD was lower in groups with longer RLDs as compared with the shortest RLD group. In longitudinal analysis, postmenopausal women with normal kidney function were followed up for 9.7 years and incident CKD occurred in 221 of 3155 (7.00%) participants. Cox analysis revealed that the risk for CKD development was significantly lower in longer RLD groups. This finding was significant even after adjustments for confounding factors. Conclusion: The risk for CKD was lower in women with longer RLDs. The amount of endogenous estrogen exposure could be a determining factor for renal function in postmenopausal women.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherElsevier/North Holland Biomedical Press-
dc.relation.isPartOfMAYO CLINIC PROCEEDINGS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHCausality-
dc.subject.MESHEstrogens / metabolism*-
dc.subject.MESHFemale-
dc.subject.MESHGlomerular Filtration Rate-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPostmenopause*-
dc.subject.MESHRenal Insufficiency, Chronic*-
dc.subject.MESHdiagnosis-
dc.subject.MESHRenal Insufficiency, Chronic*-
dc.subject.MESHepidemiology-
dc.subject.MESHReproductive Health-
dc.subject.MESHstatistics & numerical data*-
dc.subject.MESHReproductive History*-
dc.subject.MESHmethods-
dc.subject.MESHRisk Assessment-
dc.subject.MESHstatistics & numerical data-
dc.subject.MESHTime Factors-
dc.titleAssociation of Reproductive Lifespan Duration and Chronic Kidney Disease in Postmenopausal Women-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorShin Chan Kang-
dc.contributor.googleauthorJong Hyun Jhee-
dc.contributor.googleauthorYoung Su Joo-
dc.contributor.googleauthorSang Mi Lee-
dc.contributor.googleauthorKi Heon Nam-
dc.contributor.googleauthorHae-Ryong Yun-
dc.contributor.googleauthorSeung Hyeok Han-
dc.contributor.googleauthorTae-Hyun Yoo-
dc.contributor.googleauthorShin-Wook Kang-
dc.contributor.googleauthorJung Tak Park-
dc.identifier.doi10.1016/j.mayocp.2020.02.034-
dc.contributor.localIdA00053-
dc.contributor.localIdA05747-
dc.contributor.localIdA05747-
dc.contributor.localIdA01244-
dc.contributor.localIdA01244-
dc.contributor.localIdA01654-
dc.contributor.localIdA01654-
dc.contributor.localIdA02526-
dc.contributor.localIdA02526-
dc.contributor.localIdA04617-
dc.contributor.localIdA04617-
dc.contributor.localIdA05655-
dc.contributor.localIdA05655-
dc.contributor.localIdA03970-
dc.contributor.localIdA03970-
dc.contributor.localIdA04304-
dc.contributor.localIdA04304-
dc.relation.journalcodeJ03669-
dc.identifier.eissn1942-5546-
dc.identifier.pmid33168161-
dc.identifier.urlhttps://www.clinicalkey.com/#!/content/playContent/1-s2.0-S0025619620303748-
dc.contributor.alternativeNameKang, Shin Wook-
dc.contributor.affiliatedAuthor강신욱-
dc.contributor.affiliatedAuthor강신찬-
dc.contributor.affiliatedAuthor강신찬-
dc.contributor.affiliatedAuthor남기헌-
dc.contributor.affiliatedAuthor남기헌-
dc.contributor.affiliatedAuthor박정탁-
dc.contributor.affiliatedAuthor박정탁-
dc.contributor.affiliatedAuthor유태현-
dc.contributor.affiliatedAuthor유태현-
dc.contributor.affiliatedAuthor윤해룡-
dc.contributor.affiliatedAuthor윤해룡-
dc.contributor.affiliatedAuthor이상미-
dc.contributor.affiliatedAuthor이상미-
dc.contributor.affiliatedAuthor지종현-
dc.contributor.affiliatedAuthor지종현-
dc.contributor.affiliatedAuthor한승혁-
dc.contributor.affiliatedAuthor한승혁-
dc.citation.volume95-
dc.citation.number12-
dc.citation.startPage2621-
dc.citation.endPage2632-
dc.identifier.bibliographicCitationMAYO CLINIC PROCEEDINGS, Vol.95(12) : 2621-2632, 2020-12-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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