208 447

Cited 3 times in

Sex Hormone-Binding Globulin Is Associated with Obesity and Dyslipidemia in Prepubertal Children

DC Field Value Language
dc.contributor.author권아름-
dc.contributor.author김호성-
dc.contributor.author서정환-
dc.contributor.author송경철-
dc.contributor.author채현욱-
dc.date.accessioned2021-01-19T07:48:12Z-
dc.date.available2021-01-19T07:48:12Z-
dc.date.issued2020-12-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/181332-
dc.description.abstractSex hormone-binding globulin (SHBG) is associated with age, sex, and puberty. The association of SHBG with various diseases has been suggested nowadays, however, the relationships in prepubertal children have not been sufficiently investigated. This study analyzed the relationship of SHBG with body mass index (BMI) and plasma lipid levels in prepubertal children. We evaluated the association of SHBG with BMI among the 693 prepubertal children subdivided into normal, overweight, and obese groups, with plasma lipid levels among the children subdivided into normal and dyslipidemia groups. The obese and overweight group had lower SHBG levels than the normal BMI group in both sexes. The dyslipidemia group included subjects with low high-density lipoprotein cholesterol (HDL-C), high triglycerides (TG), or a high atherogenic index of plasma (AIP); this group had lower SHBG than the normal lipid group. SHBG was positively correlated with HDL-C, and negatively correlated with TG and AIP. After adjusting for BMI, SHBG was positively correlated with HDL-C and negatively correlated with TG and AIP in all groups. In conclusion, SHBG levels are closely correlated with BMI in prepubertal children. SHBG may play a meaningful role in the decrease in HDL-C and increase in TG during prepubertal age.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherMDPI AG-
dc.relation.isPartOfCHILDREN-BASEL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleSex Hormone-Binding Globulin Is Associated with Obesity and Dyslipidemia in Prepubertal Children-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.department;Dept. of Pediatrics (소아과학교실)-
dc.contributor.googleauthorGihong Park-
dc.contributor.googleauthorKyungchul Song-
dc.contributor.googleauthorYoungha Choi-
dc.contributor.googleauthorJun Suk Oh-
dc.contributor.googleauthorHan Saem Choi-
dc.contributor.googleauthorJunghwan Suh-
dc.contributor.googleauthorAhreum Kwon-
dc.contributor.googleauthorHo-Seong Kim-
dc.contributor.googleauthorHyun Wook Chae-
dc.identifier.doi10.3390/children7120272-
dc.contributor.localIdA00228-
dc.contributor.localIdA01184-
dc.contributor.localIdA05629-
dc.contributor.localIdA06013-
dc.contributor.localIdA04026-
dc.relation.journalcodeJ03917-
dc.identifier.eissn2227-9067-
dc.identifier.pmid33291623-
dc.subject.keywordchild-
dc.subject.keyworddyslipidemias-
dc.subject.keywordlipids-
dc.subject.keywordobesity-
dc.subject.keywordsex hormone-binding globulin-
dc.contributor.alternativeNameKwon, Ah Reum-
dc.contributor.affiliatedAuthor권아름-
dc.contributor.affiliatedAuthor김호성-
dc.contributor.affiliatedAuthor서정환-
dc.contributor.affiliatedAuthor송경철-
dc.contributor.affiliatedAuthor채현욱-
dc.citation.volume7-
dc.citation.number12-
dc.citation.startPage272-
dc.identifier.bibliographicCitationCHILDREN-BASEL, Vol.7(12) : 272, 2020-12-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.