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Outcomes and Associated Factors of Discrepant Coronary and Carotid Atherosclerosis

DC Field Value Language
dc.contributor.author권혁문-
dc.contributor.author김종윤-
dc.contributor.author민필기-
dc.contributor.author윤영원-
dc.contributor.author이병권-
dc.contributor.author임세중-
dc.contributor.author최의영-
dc.contributor.author홍범기-
dc.date.accessioned2020-12-11T08:10:17Z-
dc.date.available2020-12-11T08:10:17Z-
dc.date.issued2020-11-
dc.identifier.issn1349-2365-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/180801-
dc.description.abstractSome patients exhibit discrepancies in carotid and coronary artery atherosclerosis. This study aimed to define the characteristics and prognosis of these discrepant patients and determine the best strategy to detect pan-vascular atherosclerosis. A database of 5,022 consecutively registered patients who underwent both coronary angiography and carotid ultrasonography, along with clinical and blood laboratory tests, echocardiography, and pulse wave velocity (PWV), was analyzed. The development of cerebro-cardiovascular (CV) events during the follow-up period was also evaluated. A significant proportion of patients (n = 1,741, 35%) presented with a discrepancy between carotid artery plaque and coronary artery disease (CAD). In patients without carotid plaque, male sex (odds ratio [OR], 1.71; 95% confidence interval [CI], 1.20-2.41; P = 0.003), older age (OR, 1.03; 95% CI, 1.01-1.04; P = 0.002), smoking history (OR, 1.58; 95% CI, 1.13-2.20; P = 0.008), lower high-density lipoprotein (HDL) -cholesterol level (OR, 0.97; 95% CI, 0.96-0.98; P < 0.001), and lower common carotid artery end-diastolic velocity (CCA-EDV) (OR, 0.97; 95% CI, 0.95-0.99; P = 0.005) were independently related to the presence of CAD. In patients without CAD, increased PWV was independently related to the presence of carotid plaque. In survival analysis, patients with isolated CAD had a higher probability of composite CV events; those with isolated carotid plaque had a higher probability of heart failure (HF) and mortality than their counterpart groups (P < 0.05). Even in patients without carotid artery plaque, careful coronary evaluation is needed in older or male patients with smoking history, lower HDL-cholesterol level, or lower CCA-EDV. Carotid plaque may be a potential risk factor for HF.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherInternational Heart Journal Association-
dc.relation.isPartOfINTERNATIONAL HEART JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleOutcomes and Associated Factors of Discrepant Coronary and Carotid Atherosclerosis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorHyoeun Kim-
dc.contributor.googleauthorJong-Youn Kim-
dc.contributor.googleauthorPil-Ki Min-
dc.contributor.googleauthorYoung Won Yoon-
dc.contributor.googleauthorByoung Kwon Lee-
dc.contributor.googleauthorBum-Kee Hong-
dc.contributor.googleauthorSe-Joong Rim-
dc.contributor.googleauthorHyuck Moon Kwon-
dc.contributor.googleauthorEui-Young Choi-
dc.identifier.doi10.1536/ihj.20-318-
dc.contributor.localIdA00260-
dc.contributor.localIdA00926-
dc.contributor.localIdA01412-
dc.contributor.localIdA02580-
dc.contributor.localIdA02793-
dc.contributor.localIdA03372-
dc.contributor.localIdA04165-
dc.contributor.localIdA04394-
dc.relation.journalcodeJ03152-
dc.identifier.eissn1349-3299-
dc.identifier.pmid33191349-
dc.subject.keywordArterial stiffness-
dc.subject.keywordCardiovascular events-
dc.subject.keywordCoronary artery disease-
dc.subject.keywordHeart failure-
dc.contributor.alternativeNameKwon, Hyuck Moon-
dc.contributor.affiliatedAuthor권혁문-
dc.contributor.affiliatedAuthor김종윤-
dc.contributor.affiliatedAuthor민필기-
dc.contributor.affiliatedAuthor윤영원-
dc.contributor.affiliatedAuthor이병권-
dc.contributor.affiliatedAuthor임세중-
dc.contributor.affiliatedAuthor최의영-
dc.contributor.affiliatedAuthor홍범기-
dc.citation.volume61-
dc.citation.number6-
dc.citation.startPage1142-
dc.citation.endPage1149-
dc.identifier.bibliographicCitationINTERNATIONAL HEART JOURNAL, Vol.61(6) : 1142-1149, 2020-11-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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