Cited 5 times in
Completion Total Thyroidectomy Is Not Necessary for Papillary Thyroid Microcarcinoma with Occult Central Lymph Node Metastasis: A Long-Term Serial Follow-Up
DC Field | Value | Language |
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dc.contributor.author | 강상욱 | - |
dc.contributor.author | 김진경 | - |
dc.contributor.author | 남기현 | - |
dc.contributor.author | 이잔디 | - |
dc.contributor.author | 이초록 | - |
dc.contributor.author | 정웅윤 | - |
dc.contributor.author | 정종주 | - |
dc.contributor.author | 최순민 | - |
dc.date.accessioned | 2020-12-11T07:52:29Z | - |
dc.date.available | 2020-12-11T07:52:29Z | - |
dc.date.issued | 2020-10 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/180694 | - |
dc.description.abstract | The necessity of completion total thyroidectomy in patients with papillary thyroid microcarcinoma (PTMC) and pathological central lymph node metastasis (pCLNM) who underwent thyroid lobectomy with central compartment neck dissection (CCND) is unclear. We determined the necessity of completion total thyroidectomy by retrospectively comparing the prognosis according to the presence of pCLNM during a long-term follow-up. We enrolled 876 patients with PTMC who underwent thyroid lobectomy with prophylactic CCND from January 1986 to December 2009. Patients were divided according to central lymph node (CLN) metastasis: 165 (18.8%) and 711 (81.2%) in the CLN-positive and CLN-negative groups, respectively. Medical records were reviewed retrospectively, and clinicopathologic characteristics and recurrence rates were analyzed. The CLN-positive group was associated with male sex (p = 0.001), larger tumor size (p < 0.001), and more microscopic capsular invasion (p < 0.001) compared with the CLN-negative group. There was no significant difference between the two groups' recurrence (p = 0.133) or disease-free (p = 0.065) survival rates. Univariate and multivariate analyses showed no factors associated with tumor recurrence except male sex (hazard ratio = 3.043, confidence interval 1.117-8.288, p = 0.030). Patients who were diagnosed with pCLNM after undergoing thyroid lobectomy with prophylactic CCND do not require completion total thyroidectomy; however, frequent follow-up is necessary for patients with PTMC and pCLNM. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | CANCERS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Completion Total Thyroidectomy Is Not Necessary for Papillary Thyroid Microcarcinoma with Occult Central Lymph Node Metastasis: A Long-Term Serial Follow-Up | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Soon Min Choi | - |
dc.contributor.googleauthor | Jin Kyong Kim | - |
dc.contributor.googleauthor | Cho Rok Lee | - |
dc.contributor.googleauthor | Jandee Lee | - |
dc.contributor.googleauthor | Jong Ju Jeong | - |
dc.contributor.googleauthor | Kee-Hyun Nam | - |
dc.contributor.googleauthor | Woong Youn Chung | - |
dc.contributor.googleauthor | Sang-Wook Kang | - |
dc.identifier.doi | 10.3390/cancers12103032 | - |
dc.contributor.localId | A00032 | - |
dc.contributor.localId | A05739 | - |
dc.contributor.localId | A01245 | - |
dc.contributor.localId | A03066 | - |
dc.contributor.localId | A03256 | - |
dc.contributor.localId | A03674 | - |
dc.contributor.localId | A03722 | - |
dc.contributor.localId | A05941 | - |
dc.relation.journalcode | J03449 | - |
dc.identifier.eissn | 2072-6694 | - |
dc.identifier.pmid | 33081050 | - |
dc.subject.keyword | central lymph node metastasis | - |
dc.subject.keyword | completion total thyroidectomy | - |
dc.subject.keyword | papillary thyroid microcarcinoma | - |
dc.subject.keyword | recurrence | - |
dc.contributor.alternativeName | Kang, Sang Wook | - |
dc.contributor.affiliatedAuthor | 강상욱 | - |
dc.contributor.affiliatedAuthor | 김진경 | - |
dc.contributor.affiliatedAuthor | 남기현 | - |
dc.contributor.affiliatedAuthor | 이잔디 | - |
dc.contributor.affiliatedAuthor | 이초록 | - |
dc.contributor.affiliatedAuthor | 정웅윤 | - |
dc.contributor.affiliatedAuthor | 정종주 | - |
dc.contributor.affiliatedAuthor | 최순민 | - |
dc.citation.volume | 12 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 3032 | - |
dc.identifier.bibliographicCitation | CANCERS, Vol.12(10) : 3032, 2020-10 | - |
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