Cited 2 times in
Lack of association between Mannose Binding Lectin-2 gene polymorphisms and periodontitis: A meta-analysis
DC Field | Value | Language |
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dc.contributor.author | 신재일 | - |
dc.date.accessioned | 2020-12-11T07:48:48Z | - |
dc.date.available | 2020-12-11T07:48:48Z | - |
dc.date.issued | 2020-12 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/180669 | - |
dc.description.abstract | The aim of this study was to perform a meta-analysis to verify whether MBL-2 gene polymorphisms (rs1800450 and rs1800451) are associated with susceptibility to periodontitis. A search of the literature was performed for studies published before 2, March 2020 in various databases. Calculations of Odds Ratio (OR) with 95% of Confidence Intervals (CI) and heterogeneity (I2) were assessed and publication bias was calculated by Begg’ and Egger's test. The value of P < .05 was considered as significant. As results, eight articles composed the results which non-significant associations were found for all included comparisons (P > .05). Neither the mutant allele in rs1800450 polymorphisms nor the mutant allele in rs1800451 polymorphisms was associated with periodontitis (OR = 1.11, CI: 0.90–1.38, P = .33; OR = 1.01, CI: 0.75–1.35, P = .96, respectively) with no interference of I2 in these evaluations (I2 = 0%, P = .75 and I2 = 0%, P = .65, respectively) as well as in all calculations. The stratified analyses were composed by Ethnicity in Caucasian and Mixed populations and genotyping methods. In conclusion, this meta-analysis showed a non-significant association among the rs1800450 and 1,800,451 polymorphism in MBL-2 gene and periodontitis in the overall evaluation, Caucasian group and Mixed population. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | META GENE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Lack of association between Mannose Binding Lectin-2 gene polymorphisms and periodontitis: A meta-analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아청소년과학교실) | - |
dc.contributor.googleauthor | Felipe Rodolfo Pereira da Silva | - |
dc.contributor.googleauthor | Alessandro Luiz Araújo Bentes Leal | - |
dc.contributor.googleauthor | Luigi Nibali | - |
dc.contributor.googleauthor | Jae Il Shin | - |
dc.contributor.googleauthor | Marcelo Diniz Carvalho | - |
dc.contributor.googleauthor | Reyce Santos Koga | - |
dc.contributor.googleauthor | Mariana Brasil de Andrade Figueira | - |
dc.contributor.googleauthor | Juliana Gomes Galeno | - |
dc.contributor.googleauthor | Diana Mota Toro | - |
dc.contributor.googleauthor | Zinalton Gomes de Andrade | - |
dc.contributor.googleauthor | Nayana Yared Batista | - |
dc.contributor.googleauthor | José Fernando Marques Barcellos | - |
dc.identifier.doi | 10.1016/j.mgene.2020.100757 | - |
dc.contributor.localId | A02142 | - |
dc.relation.journalcode | J03961 | - |
dc.identifier.eissn | 2214-5400 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S2214540020301122 | - |
dc.subject.keyword | Genetic variation | - |
dc.subject.keyword | Mannan-binding protein | - |
dc.subject.keyword | Periodontal disease , Immune system | - |
dc.contributor.alternativeName | Shin, Jae Il | - |
dc.contributor.affiliatedAuthor | 신재일 | - |
dc.citation.volume | 26 | - |
dc.citation.startPage | 100757 | - |
dc.identifier.bibliographicCitation | META GENE, Vol.26 : 100757, 2020-12 | - |
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