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Environmental contamination in the isolation rooms of COVID-19 patients with severe pneumonia requiring mechanical ventilation or high-flow oxygen therapy

DC FieldValueLanguage
dc.contributor.author구남수-
dc.contributor.author김무현-
dc.contributor.author김정호-
dc.contributor.author백예지-
dc.contributor.author손유진-
dc.contributor.author안진영-
dc.contributor.author염준섭-
dc.contributor.author용동은-
dc.contributor.author이혁민-
dc.contributor.author정수진-
dc.contributor.author조윤숙-
dc.contributor.author최준용-
dc.contributor.author현종훈-
dc.date.accessioned2020-12-01T17:58:58Z-
dc.date.available2020-12-01T17:58:58Z-
dc.date.issued2020-11-
dc.identifier.issn0195-6701-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/180542-
dc.description.abstractBackground: Identifying the extent of environmental contamination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential for infection control and prevention. The extent of environmental contamination has not been fully investigated in the context of severe coronavirus disease (COVID-19) patients. Aim: To investigate environmental SARS-CoV-2 contamination in the isolation rooms of severe COVID-19 patients requiring mechanical ventilation or high-flow oxygen therapy. Methods: Environmental swab samples and air samples were collected from the isolation rooms of three COVID-19 patients with severe pneumonia. Patients 1 and 2 received mechanical ventilation with a closed suction system, while patient 3 received high-flow oxygen therapy and non-invasive ventilation. Real-time reverse transcription-polymerase chain reaction (rRT-PCR) was used to detect SARS-CoV-2; viral cultures were performed for samples not negative on rRT-PCR. Findings: Of the 48 swab samples collected in the rooms of patients 1 and 2, only samples from the outside surfaces of the endotracheal tubes tested positive for SARS-CoV-2 by rRT-PCR. However, in patient 3's room, 13 of the 28 environmental samples (fomites, fixed structures, and ventilation exit on the ceiling) showed positive results. Air samples were negative for SARS-CoV-2. Viable viruses were identified on the surface of the endotracheal tube of patient 1 and seven sites in patient 3's room. Conclusion: Environmental contamination of SARS-CoV-2 may be a route of viral transmission. However, it might be minimized when patients receive mechanical ventilation with a closed suction system. These findings can provide evidence for guidelines for the safe use of personal protective equipment.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherW.B. Saunders For The Hospital Infection Society-
dc.relation.isPartOfJOURNAL OF HOSPITAL INFECTION-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleEnvironmental contamination in the isolation rooms of COVID-19 patients with severe pneumonia requiring mechanical ventilation or high-flow oxygen therapy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorJ Y Ahn-
dc.contributor.googleauthorS An-
dc.contributor.googleauthorY Sohn-
dc.contributor.googleauthorY Cho-
dc.contributor.googleauthorJ H Hyun-
dc.contributor.googleauthorY J Baek-
dc.contributor.googleauthorM H Kim-
dc.contributor.googleauthorS J Jeong-
dc.contributor.googleauthorJ H Kim-
dc.contributor.googleauthorN S Ku-
dc.contributor.googleauthorJ-S Yeom-
dc.contributor.googleauthorD M Smith-
dc.contributor.googleauthorH Lee-
dc.contributor.googleauthorD Yong-
dc.contributor.googleauthorY-J Lee-
dc.contributor.googleauthorJ W Kim-
dc.contributor.googleauthorH R Kim-
dc.contributor.googleauthorJ Hwang-
dc.contributor.googleauthorJ Y Choi-
dc.identifier.doi10.1016/j.jhin.2020.08.014-
dc.contributor.localIdA00189-
dc.contributor.localIdA04521-
dc.contributor.localIdA04521-
dc.contributor.localIdA00902-
dc.contributor.localIdA00902-
dc.contributor.localIdA05921-
dc.contributor.localIdA05921-
dc.contributor.localIdA05924-
dc.contributor.localIdA05924-
dc.contributor.localIdA02267-
dc.contributor.localIdA02267-
dc.contributor.localIdA02353-
dc.contributor.localIdA02353-
dc.contributor.localIdA02423-
dc.contributor.localIdA02423-
dc.contributor.localIdA03286-
dc.contributor.localIdA03286-
dc.contributor.localIdA03638-
dc.contributor.localIdA03638-
dc.contributor.localIdA05940-
dc.contributor.localIdA05940-
dc.contributor.localIdA04191-
dc.contributor.localIdA04191-
dc.contributor.localIdA05944-
dc.contributor.localIdA05944-
dc.relation.journalcodeJ01445-
dc.identifier.eissn1532-2939-
dc.identifier.pmid32828864-
dc.subject.keywordCOVID-19-
dc.subject.keywordEnvironmental contamination-
dc.subject.keywordSARS-CoV-2-
dc.subject.keywordSevere pneumonia-
dc.contributor.alternativeNameKu, Nam Su-
dc.contributor.affiliatedAuthor구남수-
dc.contributor.affiliatedAuthor김무현-
dc.contributor.affiliatedAuthor김무현-
dc.contributor.affiliatedAuthor김정호-
dc.contributor.affiliatedAuthor김정호-
dc.contributor.affiliatedAuthor백예지-
dc.contributor.affiliatedAuthor백예지-
dc.contributor.affiliatedAuthor손유진-
dc.contributor.affiliatedAuthor손유진-
dc.contributor.affiliatedAuthor안진영-
dc.contributor.affiliatedAuthor안진영-
dc.contributor.affiliatedAuthor염준섭-
dc.contributor.affiliatedAuthor염준섭-
dc.contributor.affiliatedAuthor용동은-
dc.contributor.affiliatedAuthor용동은-
dc.contributor.affiliatedAuthor이혁민-
dc.contributor.affiliatedAuthor이혁민-
dc.contributor.affiliatedAuthor정수진-
dc.contributor.affiliatedAuthor정수진-
dc.contributor.affiliatedAuthor조윤숙-
dc.contributor.affiliatedAuthor조윤숙-
dc.contributor.affiliatedAuthor최준용-
dc.contributor.affiliatedAuthor최준용-
dc.contributor.affiliatedAuthor현종훈-
dc.contributor.affiliatedAuthor현종훈-
dc.citation.volume106-
dc.citation.number3-
dc.citation.startPage570-
dc.citation.endPage576-
dc.identifier.bibliographicCitationJOURNAL OF HOSPITAL INFECTION, Vol.106(3) : 570-576, 2020-11-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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