Cited 7 times in
Comparison of the outcomes of biliary atresia with cystic degeneration and isolated biliary atresia: A matched-pair analysis
DC Field | Value | Language |
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dc.contributor.author | 인경 | - |
dc.contributor.author | 한석주 | - |
dc.contributor.author | 호인걸 | - |
dc.date.accessioned | 2020-12-01T17:53:24Z | - |
dc.date.available | 2020-12-01T17:53:24Z | - |
dc.date.issued | 2020-10 | - |
dc.identifier.issn | 0022-3468 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/180497 | - |
dc.description.abstract | Background: Patients with biliary atresia (BA) with extrahepatic cystic degeneration (BACD) have a unique pathophysiology; however, clinical outcomes and progression of perinatal degeneration are not well-defined. We aimed to investigate the differences in clinical characteristics and outcomes between BACD and isolated BA (IBA). Methods: We performed a retrospective analysis of patients with BA who underwent Kasai portoenterostomy (KPE) from August 1997 to January 2018 and compared the clinical features and outcomes between BACD (n = 21) and IBA (n = 237). Matched-pair analysis for age and sex was performed between BACD and IBA groups to reduce confounding. Results: Before matched-pair analysis, we found that BACD patients were younger at KPE (45 vs. 64 days, p = 0.008), showed lower total bilirubin at the 3-month follow-up (0.5 vs. 1.4 mg/dL, p = 0.002), and higher 5-year native liver survival rate (95.2% vs. 61.4%, p = 0.006) than IBA patients. After matching, the BACD group showed significantly lower total bilirubin levels at the 3-month follow-up (0.5 vs. 1.5 mg/dL, p = 0.036) and higher 5-year native liver survival rate (95.2% vs. 57.5%, p = 0.006) than the IBA group. Conclusion: BACD demonstrated higher bilirubin clearance and native liver survival rates than IBA. Levels of evidence: Treatment Study, Level III. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Saunders | - |
dc.relation.isPartOf | JOURNAL OF PEDIATRIC SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Comparison of the outcomes of biliary atresia with cystic degeneration and isolated biliary atresia: A matched-pair analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Kyong Ihn | - |
dc.contributor.googleauthor | In Geol Ho | - |
dc.contributor.googleauthor | Ji Hee Lee | - |
dc.contributor.googleauthor | Younghyun Na | - |
dc.contributor.googleauthor | Dongeun Lee | - |
dc.contributor.googleauthor | Seok Joo Han | - |
dc.identifier.doi | 10.1016/j.jpedsurg.2020.02.054 | - |
dc.contributor.localId | A05505 | - |
dc.contributor.localId | A04288 | - |
dc.contributor.localId | A04706 | - |
dc.relation.journalcode | J01689 | - |
dc.identifier.eissn | 1531-5037 | - |
dc.identifier.pmid | 32192737 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0022346820301858 | - |
dc.subject.keyword | Biliary atresia | - |
dc.subject.keyword | Cystic degeneration | - |
dc.subject.keyword | Kasai portoenterostomy | - |
dc.subject.keyword | Liver fibrosis | - |
dc.subject.keyword | Matching | - |
dc.subject.keyword | Prognosis | - |
dc.contributor.alternativeName | Ihn, Kyong | - |
dc.contributor.affiliatedAuthor | 인경 | - |
dc.contributor.affiliatedAuthor | 한석주 | - |
dc.contributor.affiliatedAuthor | 호인걸 | - |
dc.citation.volume | 50 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 2177 | - |
dc.citation.endPage | 2182 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PEDIATRIC SURGERY, Vol.50(10) : 2177-2182, 2020-10 | - |
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