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Strap muscle invasion in differentiated thyroid cancer does not impact disease-specific survival: a population-based study

DC FieldValueLanguage
dc.contributor.author곽진영-
dc.contributor.author김은경-
dc.contributor.author박영진-
dc.contributor.author윤자경-
dc.contributor.author윤정현-
dc.contributor.author이잔디-
dc.date.accessioned2020-12-01T17:52:40Z-
dc.date.available2020-12-01T17:52:40Z-
dc.date.issued2020-10-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/180491-
dc.description.abstractThe American Joint Committee on Cancer (AJCC) 8th TNM staging system of differentiated thyroid cancer defines gross strap muscle invasion as T3b stage. However, the impact of strap muscle invasion on disease-specific survival (DSS) remains controversial. To elucidate the survival impact of strap muscle invasion of any degree in thyroid cancers, the Surveillance, Epidemiology, and End Results (SEER) database (1973-2018) was queried for thyroid cancer only patients on July 2019 (n = 19,914). The Cox proportional hazard analysis with multivariable adjustment revealed that strap muscle invasion was not a significant factor for DSS in tumors equal to or smaller than 40 mm (hazard ratio (HR) = 1.620 [confidence interval (CI) 0.917 - 2.860]; p = 0.097). The competing risk analysis with multivariable adjustment showed that strap muscle invasion did not significantly impact DSS regardless of tumor size or cause of death (cancer-caused death (Subdistribution HR (SDHR) = 1.567 [CI 0.984 - 2.495]; p = 0.059); deaths to other causes (SDHR = 1.155 [CI 0.842 - 1.585]; p = 0.370). A "modified" staging schema discarding strap muscle invasion as a T stage criterion showed better 10-year DSS distinction between T stages. The modified staging schema may better reflect cancer-caused death risk and may prevent potential overstaging.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherNature Publishing Group-
dc.relation.isPartOfSCIENTIFIC REPORTS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleStrap muscle invasion in differentiated thyroid cancer does not impact disease-specific survival: a population-based study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학교실)-
dc.contributor.googleauthorJa Kyung Yoon-
dc.contributor.googleauthorJandee Lee-
dc.contributor.googleauthorEun-Kyung Kim-
dc.contributor.googleauthorJung Hyun Yoon-
dc.contributor.googleauthorVivian Youngjean Park-
dc.contributor.googleauthorKyunghwa Han-
dc.contributor.googleauthorJin Young Kwak-
dc.identifier.doi10.1038/s41598-020-75161-y-
dc.contributor.localIdA00182-
dc.contributor.localIdA00801-
dc.contributor.localIdA00801-
dc.contributor.localIdA01572-
dc.contributor.localIdA01572-
dc.contributor.localIdA05487-
dc.contributor.localIdA05487-
dc.contributor.localIdA02595-
dc.contributor.localIdA02595-
dc.contributor.localIdA03066-
dc.contributor.localIdA03066-
dc.relation.journalcodeJ02646-
dc.identifier.eissn2045-2322-
dc.identifier.pmid33106498-
dc.contributor.alternativeNameKwak, Jin Young-
dc.contributor.affiliatedAuthor곽진영-
dc.contributor.affiliatedAuthor김은경-
dc.contributor.affiliatedAuthor김은경-
dc.contributor.affiliatedAuthor박영진-
dc.contributor.affiliatedAuthor박영진-
dc.contributor.affiliatedAuthor윤자경-
dc.contributor.affiliatedAuthor윤자경-
dc.contributor.affiliatedAuthor윤정현-
dc.contributor.affiliatedAuthor윤정현-
dc.contributor.affiliatedAuthor이잔디-
dc.contributor.affiliatedAuthor이잔디-
dc.citation.volume10-
dc.citation.number1-
dc.citation.startPage18248-
dc.identifier.bibliographicCitationSCIENTIFIC REPORTS, Vol.10(1) : 18248, 2020-10-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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