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Association of Snoring with Prediabetes and Type 2 Diabetes Mellitus: The Cardiovascular and Metabolic Diseases Etiology Research Center Cohort

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dc.contributor.author김현창-
dc.contributor.author심지선-
dc.contributor.author이호규-
dc.date.accessioned2020-12-01T17:50:43Z-
dc.date.available2020-12-01T17:50:43Z-
dc.date.issued2020-10-
dc.identifier.issn2233-6079-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/180479-
dc.description.abstractBackground: Evidence suggests that habitual snoring is an independent risk factor for poor glycemic health. We examined the associations between snoring with prediabetes and diabetes in Korean population. Methods: Self-reported snoring characteristics were collected from 3,948 middle-aged adults without prior cardiovascular diseases. Multivariable linear regression assessed the association of snoring intensity, frequency, disruptiveness, and disrupted breathing with fasting glucose and glycosylated hemoglobin (HbA1c) level. Then, multinomial regression evaluated how increasing snoring symptoms are associated with the risk for prediabetes and diabetes, adjusting for socioeconomic and behavioral risk factors of diabetes, obesity, hypertension, and other sleep variables. Results: Higher snoring intensity and frequency were positively associated with fasting glucose and HbA1c levels. Participants presenting the most severe snoring were at 1.84 times higher risk (95% confidence interval [CI], 1.09 to 2.29) for prediabetes and 2.24 times higher risk (95% CI, 1.84 to 2.95) for diabetes, compared to non-snorers. Such graded association was also observed amongst the most frequent snorers with higher risk for prediabetes (odds ratio [OR], 1.78; 95% CI, 1.29 to 2.22) and diabetes (OR, 2.03; 95% CI, 1.45 to 2.85). Disruptive snoring (OR, 1.60; 95% CI, 1.12 to 2.28) and near-daily disruptive breathing (OR, 2.18; 95% CI, 1.02 to 4.19) were associated with higher odds for diabetes. Such findings remained robust after additional adjustment for sleep duration, excessive daytime sleepiness, unwakefulness, and sleep-deprived driving. Conclusion: Snoring is associated with impaired glucose metabolism even in otherwise metabolically healthy adults. Habitual snorers may require lifestyle modifications and pharmacological treatment to improve glycemic profile.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Diabetes Association-
dc.relation.isPartOfDIABETES & METABOLISM JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleAssociation of Snoring with Prediabetes and Type 2 Diabetes Mellitus: The Cardiovascular and Metabolic Diseases Etiology Research Center Cohort-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Preventive Medicine and Public Health (예방의학교실)-
dc.contributor.googleauthorSo Mi Jemma Cho-
dc.contributor.googleauthorHokyou Lee-
dc.contributor.googleauthorJee-Seon Shim-
dc.contributor.googleauthorHyeon Chang Kim-
dc.identifier.doi10.4093/dmj.2019.0128-
dc.contributor.localIdA01142-
dc.contributor.localIdA02212-
dc.contributor.localIdA05838-
dc.relation.journalcodeJ00720-
dc.identifier.eissn2233-6087-
dc.identifier.pmid32431103-
dc.subject.keywordPrediabetic state-
dc.subject.keywordSnoring-
dc.subject.keywordDiabetes mellitus, type 2-
dc.contributor.alternativeNameKim, Hyeon Chang-
dc.contributor.affiliatedAuthor김현창-
dc.contributor.affiliatedAuthor심지선-
dc.contributor.affiliatedAuthor이호규-
dc.citation.volume44-
dc.citation.number5-
dc.citation.startPage687-
dc.citation.endPage698-
dc.identifier.bibliographicCitationDIABETES & METABOLISM JOURNAL, Vol.44(5) : 687-698, 2020-10-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학교실) > 1. Journal Papers

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