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Comparison of olfactory and taste functions between eosinophilic and non-eosinophilic chronic rhinosinusitis

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dc.contributor.author김창훈-
dc.contributor.author윤주헌-
dc.contributor.author조형주-
dc.contributor.author하종균-
dc.date.accessioned2020-12-01T17:47:17Z-
dc.date.available2020-12-01T17:47:17Z-
dc.date.issued2020-10-
dc.identifier.issn0385-8146-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/180452-
dc.description.abstractObjective: Most patients with chronic rhinosinusitis (CRS) complain of olfactory and/or taste dysfunctions. However, olfactory and taste dysfunctions depending on the subtype of CRS, classified as eosinophilic CRS (ECRS) and non-eosinophilic CRS (NCRS), have not been clearly reported. Therefore, the purpose of this study was to investigate the clinical features in olfactory and taste functions according to the subtype classified as ECRS and NCRS. Methods: We retrospectively analyzed the electronic medical records of patients who underwent endoscopic sinus surgery and were diagnosed with CRS. The patients were divided into ECRS and NCRS groups, according to their Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC) scores. We analyzed demographic characteristics, Sino-Nasal Outcome Test findings, Lund-Mackay score, and the results of previously-validated tests, including the Korean Version of Sniffin' Stick test and chemical gustatory function test. Results: Patients with ECRS and NCRS had decreased olfactory and taste functions compared to the control group. In particular, the olfactory score of ECRS patients was lower than that of NCRS patients (18.1 ± 9.5 vs 23.7 ± 8.5, respectively, p <0.001). On the other hand, taste scores of ECRS patients were not statistically different compared to NCRS patients (19.1 ± 4.7 vs. 18.3 ± 4.7, respectively, p = 0.166). Olfactory score decreased with increase in JESREC score (r=-0.203, p = 0.002), but it had no correlation with taste score (r = 0.072, p = 0.276). Conclusion: We found a difference in olfactory function but no difference in taste function between patients in ECRS and NCRS groups. These results may provide valuable clinical features in terms of olfactory and taste functions according to the subtypes of CRS.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherElsevier Science-
dc.relation.isPartOfAURIS NASUS LARYNX-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleComparison of olfactory and taste functions between eosinophilic and non-eosinophilic chronic rhinosinusitis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Otorhinolaryngology (이비인후과학교실)-
dc.contributor.googleauthorSang Hyeon Ahn-
dc.contributor.googleauthorEun Jung Lee-
dc.contributor.googleauthorJong-Gyun Ha-
dc.contributor.googleauthorChi Sang Hwang-
dc.contributor.googleauthorJoo-Heon Yoon-
dc.contributor.googleauthorChang-Hoon Kim-
dc.contributor.googleauthorHyung-Ju Cho-
dc.identifier.doi10.1016/j.anl.2020.04.006-
dc.contributor.localIdA01050-
dc.contributor.localIdA02604-
dc.contributor.localIdA03936-
dc.contributor.localIdA04810-
dc.relation.journalcodeJ00263-
dc.identifier.eissn1879-1476-
dc.identifier.pmid32386824-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0385814620300869-
dc.subject.keywordChronic rhinosinusitis-
dc.subject.keywordEosinophil-
dc.subject.keywordJESREC score-
dc.subject.keywordOlfaction-
dc.subject.keywordTaste-
dc.contributor.alternativeNameKim, Chang Hoon-
dc.contributor.affiliatedAuthor김창훈-
dc.contributor.affiliatedAuthor윤주헌-
dc.contributor.affiliatedAuthor조형주-
dc.contributor.affiliatedAuthor하종균-
dc.citation.volume47-
dc.citation.number5-
dc.citation.startPage820-
dc.citation.endPage827-
dc.identifier.bibliographicCitationAURIS NASUS LARYNX, Vol.47(5) : 820-827, 2020-10-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers

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