Cited 10 times in
Clinical Impact of Combined Modified Glasgow Prognostic Score and C-Reactive Protein/Albumin Ratio in Patients with Colorectal Cancer
DC Field | Value | Language |
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dc.contributor.author | 강정현 | - |
dc.contributor.author | 박은정 | - |
dc.contributor.author | 백승혁 | - |
dc.contributor.author | 신수진 | - |
dc.contributor.author | 이강영 | - |
dc.date.accessioned | 2020-12-01T17:37:30Z | - |
dc.date.available | 2020-12-01T17:37:30Z | - |
dc.date.issued | 2020-10 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/180354 | - |
dc.description.abstract | The prognostic impact of the combination of the modified Glasgow prognostic score (mGPS) and C-reactive protein/albumin ratio (CAR) in colorectal cancer (CRC) is unclear. We aimed to investigate the clinical usefulness of this combination as a predictor of survival in CRC patients. We retrospectively evaluated 769 CRC patients who had undergone surgery between January 2006 and March 2014. The CAR and mGPS within 1 month postoperation were examined. The integrated area under the curve (iAUC) was compared among mGPS, CAR, and the combined classification (CC). The optimal CAR cut-off for discriminating overall survival was 0.14. Based on this cut-off, the mGPS 0 group was divided into the mGPS 0 with low CAR and the mGPS 0 with high CAR groups, whereas all mGPS 1 and 2 patients were classified into the high CAR group. CC was an independent prognostic factor, and its iAUC value (0.587, 95% CI 0.553-0.624) was superior to those of the mGPS (0.544, 95% CI 0.516-0.576) (bootstrap iAUC mean difference = 0.043; 95% CI = 0.015-0.072) and CAR (0.578, 95% CI 0.545-0.613) (bootstrap iAUC mean difference = 0.009; 95% CI = 0.002-0.017), respectively. In conclusion, the combination of mGPS and CAR has a synergistic effect and has a higher prognostic accuracy than mGPS or CAR alone in patients with CRC. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI AG | - |
dc.relation.isPartOf | DIAGNOSTICS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Clinical Impact of Combined Modified Glasgow Prognostic Score and C-Reactive Protein/Albumin Ratio in Patients with Colorectal Cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Woosung Son | - |
dc.contributor.googleauthor | Su-Jin Shin | - |
dc.contributor.googleauthor | Su Hyeong Park | - |
dc.contributor.googleauthor | Soo Kyung Lee | - |
dc.contributor.googleauthor | Eun Jung Park | - |
dc.contributor.googleauthor | Seung Hyuk Baik | - |
dc.contributor.googleauthor | Kang Young Lee | - |
dc.contributor.googleauthor | Jeonghyun Kang | - |
dc.identifier.doi | 10.3390/diagnostics10110859 | - |
dc.contributor.localId | A00080 | - |
dc.contributor.localId | A04572 | - |
dc.contributor.localId | A01827 | - |
dc.contributor.localId | A04596 | - |
dc.contributor.localId | A02640 | - |
dc.relation.journalcode | J03798 | - |
dc.identifier.eissn | 2075-4418 | - |
dc.identifier.pmid | 33105743 | - |
dc.subject.keyword | C-reactive protein/albumin ratio | - |
dc.subject.keyword | colorectal cancer | - |
dc.subject.keyword | integrated area under the curve | - |
dc.subject.keyword | modified glasgow prognostic score | - |
dc.subject.keyword | survival | - |
dc.contributor.alternativeName | Kang, Jeonghyun | - |
dc.contributor.affiliatedAuthor | 강정현 | - |
dc.contributor.affiliatedAuthor | 박은정 | - |
dc.contributor.affiliatedAuthor | 백승혁 | - |
dc.contributor.affiliatedAuthor | 신수진 | - |
dc.contributor.affiliatedAuthor | 이강영 | - |
dc.citation.volume | 10 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | E859 | - |
dc.identifier.bibliographicCitation | DIAGNOSTICS, Vol.10(11) : E859, 2020-10 | - |
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