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Descriptive Analysis of Histiocytic and Dendritic Cell Neoplasms: A Single-Institution Experience
DC Field | Value | Language |
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dc.contributor.author | 김혜민 | - |
dc.contributor.author | 양우익 | - |
dc.contributor.author | 유철주 | - |
dc.contributor.author | 윤선옥 | - |
dc.contributor.author | 한승민 | - |
dc.date.accessioned | 2020-12-01T17:35:14Z | - |
dc.date.available | 2020-12-01T17:35:14Z | - |
dc.date.issued | 2020-09 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/180338 | - |
dc.description.abstract | Purpose: Histiocytic and dendritic cell neoplasms are rare hematologic tumors. This study aimed to describe the epidemiologic features of the entire spectrum of histiocytic and dendritic cell neoplasms, including clinicopathological variables and patient outcomes. Materials and methods: We comprehensively reviewed 274 patients who were diagnosed with histiocytic and dendritic neoplasms at Severance Hospital, Seoul, South Korea between 1995 and 2018. Results: The most common neoplasm was Langerhans cell histiocytosis (LCH), followed by dermal xanthogranuloma. Among non-LCH sarcomas, histiocytic sarcoma (HS) showed a relatively high prevalence, followed by follicular dendritic cell sarcoma (FDCS). Disseminated juvenile xanthogranuloma (DJG), Erdheim-Chester disease (ECD), indeterminate dendritic cell tumor (IDCT), and interdigitating dendritic cell sarcoma (IDCS) rarely occurred. Generally, these tumors presented in childhood, although the non-LCH sarcoma (HS/FDCS/IDCS/IDCT) group of tumors and ECD occurred in late adulthood. Multiorgan involvement and advanced Ann-Arbor stage, as well as recurrence and death of disease, were not uncommon. The non-LCH sarcoma group had the worst overall survival, compared to the DJG, ECD, and LCH groups. Conclusion: Our findings indicate that histiocytic and dendritic cell neoplasms exhibit heterogeneous epidemiologic characteristics and that some patients may have unfavorable outcomes, especially those with non-LCH sarcoma. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Yonsei University | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Dendritic Cell Sarcoma, Follicular / epidemiology | - |
dc.subject.MESH | Dendritic Cell Sarcoma, Follicular / pathology | - |
dc.subject.MESH | Dendritic Cells / pathology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Histiocytes / pathology* | - |
dc.subject.MESH | Histiocytic Disorders, Malignant / epidemiology | - |
dc.subject.MESH | Histiocytic Disorders, Malignant / pathology* | - |
dc.subject.MESH | Histiocytic Sarcoma / epidemiology | - |
dc.subject.MESH | Histiocytic Sarcoma / pathology* | - |
dc.subject.MESH | Histiocytosis, Langerhans-Cell / epidemiology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neoplasm Recurrence, Local / pathology | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Republic of Korea / epidemiology | - |
dc.subject.MESH | Seoul | - |
dc.subject.MESH | Xanthogranuloma, Juvenile / epidemiology | - |
dc.subject.MESH | Xanthogranuloma, Juvenile / pathology | - |
dc.title | Descriptive Analysis of Histiocytic and Dendritic Cell Neoplasms: A Single-Institution Experience | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pathology (병리학교실) | - |
dc.contributor.googleauthor | Hye Min Kim | - |
dc.contributor.googleauthor | Woo Ick Yang | - |
dc.contributor.googleauthor | Chuhl Joo Lyu | - |
dc.contributor.googleauthor | Seung Min Hahn | - |
dc.contributor.googleauthor | Sun Och Yoon | - |
dc.identifier.doi | 10.3349/ymj.2020.61.9.774 | - |
dc.contributor.localId | A04553 | - |
dc.contributor.localId | A02300 | - |
dc.contributor.localId | A02524 | - |
dc.contributor.localId | A02566 | - |
dc.contributor.localId | A04299 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 32882761 | - |
dc.subject.keyword | Histiocytic disorders | - |
dc.subject.keyword | dendritic cells | - |
dc.subject.keyword | epidemiology | - |
dc.subject.keyword | malignant | - |
dc.contributor.alternativeName | Kim, Hye Min | - |
dc.contributor.affiliatedAuthor | 김혜민 | - |
dc.contributor.affiliatedAuthor | 양우익 | - |
dc.contributor.affiliatedAuthor | 유철주 | - |
dc.contributor.affiliatedAuthor | 윤선옥 | - |
dc.contributor.affiliatedAuthor | 한승민 | - |
dc.citation.volume | 61 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 774 | - |
dc.citation.endPage | 779 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.61(9) : 774-779, 2020-09 | - |
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