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Risk of Bronchial Dehiscence in Lung Transplant Recipients With Carbapenemase-producing Klebsiella

DC FieldValueLanguage
dc.contributor.author김송이-
dc.contributor.author박무석-
dc.contributor.author백효채-
dc.contributor.author서지원-
dc.contributor.author이진구-
dc.contributor.author정수진-
dc.date.accessioned2020-12-01T17:21:42Z-
dc.date.available2020-12-01T17:21:42Z-
dc.date.issued2020-07-
dc.identifier.issn0003-4975-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/180233-
dc.description.abstractBackground: Klebsiella pneumoniae is commonly isolated after lung transplantation. This study observed an increase in bronchial complications after an outbreak of Klebsiella pneumoniae carbapenemase-producing Klebsiella (KPC-KP). Methods: The study enrolled 173 patients who had undergone bilateral lung transplantation between 2012 and 2018 to examine the association between bronchial complications after lung transplantation and KPC-KP. The KPC-KP group was defined as patients whose isolates from sputum or bronchoalveolar lavage fluid were positive for KPC-KP. The presence of bronchial complications was defined as a positive finding on bronchoscopy in accordance with the criteria of the International Society for Heart and Lung Transplantation. Risk factors for bronchial complications were analyzed. Results: KPC-KP was identified in 29 patients (16.8%), and bronchial dehiscence was observed in 13 patients (7.5%). Smoking (odds ratio [OR], 5.690; 95% confidence interval [CI], 1.106- to 9.260; P = .037), the presence of KPC-KP (OR, 5.360; 95% CI, 1.380 to 20.810; P = .015), and bronchial necrosis (OR, 7.009; 95% CI, 1.811 to 27.124; P = .005) were associated with bronchial dehiscence in a multivariate logistic regression model. Conclusions: The presence of KPC-KP in lung-transplant recipients significantly increased the risk of bronchial dehiscence, independent of bronchial necrosis. Thus, patients with KPC-KP require greater surveillance and follow-up bronchoscopy, irrespective of the presence or absence of bronchial necrosis or the overall patient condition.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherElsevier-
dc.relation.isPartOfANNALS OF THORACIC SURGERY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAged-
dc.subject.MESHBacterial Proteins-
dc.subject.MESHBronchial Diseases / diagnosis-
dc.subject.MESHBronchial Diseases / epidemiology*-
dc.subject.MESHBronchial Diseases / microbiology-
dc.subject.MESHBronchoscopy-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHIncidence-
dc.subject.MESHKlebsiella Infections / diagnosis-
dc.subject.MESHKlebsiella Infections / epidemiology*-
dc.subject.MESHKlebsiella pneumoniae*-
dc.subject.MESHLung Diseases / surgery*-
dc.subject.MESHLung Transplantation / adverse effects*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHSurgical Wound Dehiscence / diagnosis-
dc.subject.MESHSurgical Wound Dehiscence / epidemiology*-
dc.subject.MESHSurgical Wound Dehiscence / microbiology-
dc.subject.MESHbeta-Lactamases-
dc.titleRisk of Bronchial Dehiscence in Lung Transplant Recipients With Carbapenemase-producing Klebsiella-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorJee Won Suh-
dc.contributor.googleauthorJin Gu Lee-
dc.contributor.googleauthorSu Jin Jeong-
dc.contributor.googleauthorMoo Suk Park-
dc.contributor.googleauthorSong Yee Kim-
dc.contributor.googleauthorHyo Chae Paik-
dc.identifier.doi10.1016/j.athoracsur.2020.01.076-
dc.contributor.localIdA00626-
dc.contributor.localIdA01457-
dc.contributor.localIdA01457-
dc.contributor.localIdA01846-
dc.contributor.localIdA01846-
dc.contributor.localIdA04956-
dc.contributor.localIdA04956-
dc.contributor.localIdA03225-
dc.contributor.localIdA03225-
dc.contributor.localIdA03638-
dc.contributor.localIdA03638-
dc.relation.journalcodeJ00183-
dc.identifier.eissn1552-6259-
dc.identifier.pmid32151582-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0003497520303465-
dc.contributor.alternativeNameKim, Song Yee-
dc.contributor.affiliatedAuthor김송이-
dc.contributor.affiliatedAuthor박무석-
dc.contributor.affiliatedAuthor박무석-
dc.contributor.affiliatedAuthor백효채-
dc.contributor.affiliatedAuthor백효채-
dc.contributor.affiliatedAuthor서지원-
dc.contributor.affiliatedAuthor서지원-
dc.contributor.affiliatedAuthor이진구-
dc.contributor.affiliatedAuthor이진구-
dc.contributor.affiliatedAuthor정수진-
dc.contributor.affiliatedAuthor정수진-
dc.citation.volume110-
dc.citation.number1-
dc.citation.startPage265-
dc.citation.endPage271-
dc.identifier.bibliographicCitationANNALS OF THORACIC SURGERY, Vol.110(1) : 265-271, 2020-07-
dc.identifier.rimsid67188-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

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