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Diabetic polyneuropathy and the risk of developing carpal tunnel syndrome: A nationwide, population-based study

Authors
 Hyun Im Moon  ;  Jaeyong Shin  ;  Yong Wook Kim  ;  Jee Suk Chang  ;  SeoYeon Yoon 
Citation
 MUSCLE & NERVE, Vol.62(2) : 208-213, 2020-08 
Journal Title
 MUSCLE & NERVE 
ISSN
 0148-639X 
Issue Date
2020-08
MeSH
Adult ; Age Factors ; Aged ; Carpal Tunnel Syndrome / epidemiology* ; Diabetes Mellitus, Type 1 / complications ; Diabetes Mellitus, Type 1 / epidemiology* ; Diabetes Mellitus, Type 2 / complications ; Diabetes Mellitus, Type 2 / epidemiology* ; Diabetic Neuropathies / epidemiology* ; Diabetic Neuropathies / etiology ; Female ; Humans ; Male ; Middle Aged ; Proportional Hazards Models ; Republic of Korea / epidemiology ; Risk ; Sex Factors
Keywords
carpal tunnel syndrome ; diabetes ; diabetic polyneuropathy ; population-based cohort
Abstract
Background: We investigated the risk of carpal tunnel syndrome (CTS) in diabetic polyneuropathy (DPN). Methods: This study was conducted using records from the National Health Insurance System (NHIS). We divided patients diagnosed with diabetes mellitus (DM) into those with and without DPN. We assessed the effect of DPN on the risk of CTS using Cox proportional hazards regression analyses. Results: DPN was associated with an increased risk of CTS (hazard ratio [HR], 1.33; 95% confidence interval [CI], 1.12-1.58). In sub-analyses, female gender (HR, 1.45; 95% CI, 1.20-1.76), presence of type 2 DM (HR, 1.36; 95% CI, 1.11-1.64), and age 35 to 64 years (HR 1.35; 95% CI, 1.11-1.64) were significantly associated with an increased risk of CTS. Conclusions: Patients with DPN had an increased risk of CTS compared with the non-DPN group, particularly females, those with type 2 DM, and those aged 35 to 64 years.
Full Text
https://onlinelibrary.wiley.com/doi/full/10.1002/mus.26901
DOI
10.1002/mus.26901
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Kim, Yong Wook(김용욱) ORCID logo https://orcid.org/0000-0002-5234-2454
Chang, Jee Suk(장지석) ORCID logo https://orcid.org/0000-0001-7685-3382
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/180190
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