15 35

Cited 0 times in

임상검사실에서의 액체크로마토그래피-질량분석을 위한 권고안: 제3편. 질 보증

DC FieldValueLanguage
dc.contributor.author이상국-
dc.date.accessioned2020-12-01T16:47:18Z-
dc.date.available2020-12-01T16:47:18Z-
dc.date.issued2020-07-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/179974-
dc.description.abstractThe use of liquid chromatography-tandem mass spectrometry (LC-MS/MS) in clinical laboratories is increasing and is likely to expand into even more clinical venues in the future. Mass spectrometry is the standard method for analyte identification in the clinical chemistry field; however, differences in mass spectrometry protocols and handling affect the accuracy and reliability of these tests and prevent direct comparisons of results between laboratories. For example, the results of laboratories using LC-MS/MS methods are less likely to be reproducible than those of laboratories using conventional, automated methods. This is due to inadequate handling of the equipment and/or poor quality control after the implementation of the method, which may result in unnecessary medical expenditures or even adverse outcomes for the patients. Unfortunately, guidelines to monitor the accuracy of LC-MS/MS-based clinical tests are still lacking. In general, the quality control methods used in conventional clinical tests could also be applied to LC-MS/MS. However, additional quality control methods specific to LC-MS/MS techniques must be continuously employed to maintain the same quality level achieved during method development and verification. This report is intended to help clinical laboratories that operate LC-MS/MS improve the accuracy and reliability of their testing by providing guidance for quality assurance and improvement, based on a collection of existing guidelines and expert opinions from the literature.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean-
dc.publisherKorean Society for Laboratory Medicine-
dc.relation.isPartOfLaboratory Medicine Online-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.title임상검사실에서의 액체크로마토그래피-질량분석을 위한 권고안: 제3편. 질 보증-
dc.title.alternativeRecommendations for Liquid Chromatography-Mass Spectrometry in the Clinical Laboratory: Part III. Quality Assurance-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학교실)-
dc.contributor.googleauthor김세림-
dc.contributor.googleauthor이상국-
dc.contributor.googleauthor문수영-
dc.contributor.googleauthor박형두-
dc.contributor.googleauthor송상훈-
dc.contributor.googleauthor이경훈-
dc.contributor.googleauthor최현정-
dc.contributor.googleauthor이수연-
dc.contributor.googleauthor대한임상화학회 임상질량분석연구위원회-
dc.identifier.doi10.3343/lmo.2020.10.3.185-
dc.contributor.localIdA02810-
dc.relation.journalcodeJ02151-
dc.identifier.eissn2093-6338-
dc.subject.keywordLiquid chromatography-tandem mass spectrometry-
dc.subject.keywordRecommendation-
dc.subject.keywordClinical testing-
dc.subject.keywordQuality assurance-
dc.subject.keywordQuality control-
dc.subject.keywordPost-implementation monitoring-
dc.subject.keywordClinical laboratories-
dc.contributor.alternativeNameLee, Sang Guk-
dc.contributor.affiliatedAuthor이상국-
dc.citation.volume10-
dc.citation.number3-
dc.citation.startPage185-
dc.citation.endPage196-
dc.identifier.bibliographicCitationLaboratory Medicine Online, Vol.10(3) : 185-196, 2020-07-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.