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18F-AV-1451 PET Imaging in Three Patients with Probable Cerebral Amyloid Angiopathy

DC FieldValueLanguage
dc.contributor.author조한나-
dc.contributor.author최재용-
dc.contributor.author유영훈-
dc.contributor.author류철형-
dc.date.accessioned2020-11-17T05:02:52Z-
dc.date.available2020-11-17T05:02:52Z-
dc.date.issued2017-
dc.identifier.issn1387-2877-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/179867-
dc.description.abstractCerebrovascular deposition of amyloid-β, known as cerebral amyloid angiopathy (CAA), is associated with MRI findings of lobar hemorrhage, cerebral microbleeds, and cortical superficial siderosis. Although pathological studies suggest that tau may co-localize with vascular amyloid, this has not yet been investigated in CAA in vivo. Three patients with probable CAA underwent 11C-Pittsburgh Compound B (PiB) PET or 18F-florbetaben PET to evaluate amyloid burden, and 18F-AV-1451 PET to evaluate paired helical filament tau burden. Regions that had cerebral microbleeds or cortical superficial siderosis largely overlapped with those showing increased 18F-AV-1451. Our preliminary study raised the possibility that lobar cerebral microbleeds, and cortical superficial siderosis, which are characteristic markers of vascular amyloid, may be associated with local production of paired helical filament tau.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherIOS Press-
dc.relation.isPartOfJOURNAL OF ALZHEIMERS DISEASE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHAniline Compounds / metabolism-
dc.subject.MESHBrain / diagnostic imaging*-
dc.subject.MESHCarbolines / metabolism*-
dc.subject.MESHCerebral Amyloid Angiopathy / diagnostic imaging*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHImage Processing, Computer-Assisted-
dc.subject.MESHMale-
dc.subject.MESHPositron-Emission Tomography*-
dc.subject.MESHThiazoles / metabolism-
dc.title18F-AV-1451 PET Imaging in Three Patients with Probable Cerebral Amyloid Angiopathy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurology (신경과학교실)-
dc.contributor.googleauthorHee Jin Kim-
dc.contributor.googleauthorHanna Cho-
dc.contributor.googleauthorDavid J Werring-
dc.contributor.googleauthorYoung Kyoung Jang-
dc.contributor.googleauthorYeo Jin Kim-
dc.contributor.googleauthorJin San Lee-
dc.contributor.googleauthorJuyoun Lee-
dc.contributor.googleauthorSoomin Jun-
dc.contributor.googleauthorSeongbeom Park-
dc.contributor.googleauthorYoung Hoon Ryu-
dc.contributor.googleauthorJae Yong Choi-
dc.contributor.googleauthorYoung Seok Cho-
dc.contributor.googleauthorSeung Hwan Moon-
dc.contributor.googleauthorDuk L Na-
dc.contributor.googleauthorChul Hyoung Lyoo-
dc.contributor.googleauthorSang Won Seo-
dc.identifier.doi10.3233/JAD-161139-
dc.contributor.localIdA03920-
dc.contributor.localIdA04695-
dc.contributor.localIdA04695-
dc.contributor.localIdA02485-
dc.contributor.localIdA02485-
dc.contributor.localIdA01333-
dc.contributor.localIdA01333-
dc.relation.journalcodeJ01231-
dc.identifier.eissn1875-8908-
dc.identifier.pmid28282808-
dc.identifier.urlhttps://content.iospress.com/articles/journal-of-alzheimers-disease/jad161139-
dc.subject.keyword18F-AV-1451 PET-
dc.subject.keywordCerebral amyloid angiopathy-
dc.subject.keywordcortical superficial siderosis-
dc.subject.keywordlobar cerebral microbleeds-
dc.subject.keywordtau-
dc.contributor.alternativeNameCho, Hanna-
dc.contributor.affiliatedAuthor조한나-
dc.contributor.affiliatedAuthor최재용-
dc.contributor.affiliatedAuthor최재용-
dc.contributor.affiliatedAuthor유영훈-
dc.contributor.affiliatedAuthor유영훈-
dc.contributor.affiliatedAuthor류철형-
dc.contributor.affiliatedAuthor류철형-
dc.citation.volume57-
dc.citation.number3-
dc.citation.startPage711-
dc.citation.endPage716-
dc.identifier.bibliographicCitationJOURNAL OF ALZHEIMERS DISEASE, Vol.57(3) : 711-716, 2017-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers

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