Cited 2 times in
Short-term Outcomes After Upfront Chemotherapy Followed by Curative Surgery in Metastatic Colon Cancer: A Comparison With Upfront Surgery Patients
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 한명현 | - |
dc.contributor.author | 한윤대 | - |
dc.contributor.author | 조민수 | - |
dc.contributor.author | 허혁 | - |
dc.contributor.author | 민병소 | - |
dc.contributor.author | 이강영 | - |
dc.contributor.author | 김남규 | - |
dc.date.accessioned | 2020-11-05T07:20:47Z | - |
dc.date.available | 2020-11-05T07:20:47Z | - |
dc.date.issued | 2019-12 | - |
dc.identifier.issn | 2287-9714 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/179822 | - |
dc.description.abstract | Purpose: Upfront systemic chemotherapy with target agents has been recommended for patients with stage IV colon cancer. Some with partial response are considered for curative resection. There is high risk of developing postoperative complications following upfront systemic chemotherapy. We aimed to evaluate short-term perioperative outcomes of curative surgery after upfront chemotherapy in comparison with upfront surgery in patients with metastatic colon cancer. Methods: Between January 2010 and October 2015, 146 patients (80 in the surgery first group, 66 in the upfront chemotherapy group) who underwent surgical resection before or after systemic chemotherapy for metastatic colon cancer were included in the present study. All decisions for treatment were made through a multidisciplinary team. Postoperative clinical outcomes and complications were analyzed to compare the groups. Results: There was no difference between the 2 groups in terms of postoperative clinical outcomes. Overall complication rates were not different between the groups (surgery first group: 46.3% vs. upfront chemotherapy group: 60.6%; P = 0.084). When classified according to the Clavien-Dindo method, there was no difference between the 2 groups in terms of major complications (grade 3 or more) (surgery first group: 18.9% vs. upfront chemotherapy group: 27.5%; P = 0.374). Conclusion: There was no significant increase in major postoperative complications in metastatic colon cancer patients who received upfront chemotherapy followed by curative surgery. Careful patient selection and treatment planning are important. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Society of Coloproctology | - |
dc.relation.isPartOf | ANNALS OF COLOPROCTOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Short-term Outcomes After Upfront Chemotherapy Followed by Curative Surgery in Metastatic Colon Cancer: A Comparison With Upfront Surgery Patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Myung Hyun Han | - |
dc.contributor.googleauthor | Youn Young Park | - |
dc.contributor.googleauthor | Shiva Pratap | - |
dc.contributor.googleauthor | Yoon Dae Han | - |
dc.contributor.googleauthor | Min Soo Cho | - |
dc.contributor.googleauthor | Hyuk Hur | - |
dc.contributor.googleauthor | Byung Soh Min | - |
dc.contributor.googleauthor | Kang Young Lee | - |
dc.contributor.googleauthor | Nam Kyu Kim | - |
dc.identifier.doi | 10.3393/ac.2019.03.04.1 | - |
dc.contributor.localId | A05063 | - |
dc.contributor.localId | A04313 | - |
dc.contributor.localId | A03817 | - |
dc.contributor.localId | A04373 | - |
dc.contributor.localId | A01402 | - |
dc.contributor.localId | A02640 | - |
dc.contributor.localId | A00353 | - |
dc.relation.journalcode | J00157 | - |
dc.identifier.eissn | 2287-9722 | - |
dc.identifier.pmid | 31937072 | - |
dc.subject.keyword | Antineoplastic agents | - |
dc.subject.keyword | Colonic neoplasms | - |
dc.subject.keyword | Neoplasm metastasis | - |
dc.subject.keyword | Postoperative complications | - |
dc.contributor.alternativeName | Han, Myung Hyun | - |
dc.contributor.affiliatedAuthor | 한명현 | - |
dc.contributor.affiliatedAuthor | 한윤대 | - |
dc.contributor.affiliatedAuthor | 조민수 | - |
dc.contributor.affiliatedAuthor | 허혁 | - |
dc.contributor.affiliatedAuthor | 민병소 | - |
dc.contributor.affiliatedAuthor | 이강영 | - |
dc.contributor.affiliatedAuthor | 김남규 | - |
dc.citation.volume | 35 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 327 | - |
dc.citation.endPage | 334 | - |
dc.identifier.bibliographicCitation | ANNALS OF COLOPROCTOLOGY, Vol.35(6) : 327-334, 2019-12 | - |
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