Cited 3 times in
Echocardiographic parameters determining cardiovascular outcomes in patients after acute ischemic stroke
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김민관 | - |
dc.contributor.author | 백순명 | - |
dc.contributor.author | 정재호 | - |
dc.date.accessioned | 2020-11-04T01:03:21Z | - |
dc.date.available | 2020-11-04T01:03:21Z | - |
dc.date.issued | 2020-08 | - |
dc.identifier.issn | 1569-5794 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/179802 | - |
dc.description.abstract | Previous studies have focused on only 1 or 2 echocardiographic parameters as prognostic markers in patients with acute ischemic stroke (AIS). A total of 900 patients with AIS who underwent transthoracic echocardiography (72.6 ± 12.0 years and 60% males) were retrospectively reviewed. Composite clinical events, including all-cause mortality, non-fatal stroke, non-fatal myocardial infarction, and coronary revascularization, were assessed during clinical follow-ups. During a median follow-up of 3.3 years (interquartile range 0.6-5.1 years), there were 151 (16.8%) composite events. In the multivariable analyses after controlling for potential confounders, left ventricular ejection fraction (LVEF) < 62% (hazard ratio [HR] 1.62; 95% confidence interval [CI] 1.14-2.30; p = 0.007) and AV sclerosis (AVs) (HR 1.56; 95% CI 1.10-2.21; p = 0.013) were independent prognostic factors associated with composite events. Multivariable analyses showed that HR for composite events gradually increased according to LVEF and AVs: HR was 2.6-fold higher in the highest-risk group than in the lowest group (p < 0.001). Compared with a clinical model (global chi-square = 69.6), LVEF, AVs, and both of them were significantly improved outcome prediction in sequential Cox model analysis (global chi-square = 75.6, 75.7, and 78.8, respectively; p < 0.05 for each) for each. In patients with AIS, LVEF < 62%, and the presence of AV sclerosis can predict future vascular events. Patients with AIS exhibiting reduced LVEF and AV sclerosis may benefit from aggressive secondary prevention. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Kluwer Academic Publishers | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Aortic Valve / diagnostic imaging* | - |
dc.subject.MESH | Aortic Valve / physiopathology | - |
dc.subject.MESH | Brain Ischemia / diagnostic imaging | - |
dc.subject.MESH | Brain Ischemia / mortality | - |
dc.subject.MESH | Brain Ischemia / therapy* | - |
dc.subject.MESH | Cause of Death | - |
dc.subject.MESH | Echocardiography, Doppler, Color* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Heart Valve Diseases / diagnostic imaging* | - |
dc.subject.MESH | Heart Valve Diseases / mortality | - |
dc.subject.MESH | Heart Valve Diseases / physiopathology | - |
dc.subject.MESH | Heart Valve Diseases / therapy | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Sclerosis | - |
dc.subject.MESH | Stroke / diagnostic imaging | - |
dc.subject.MESH | Stroke / mortality | - |
dc.subject.MESH | Stroke / therapy* | - |
dc.subject.MESH | Stroke Volume | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Ventricular Dysfunction, Left / diagnostic imaging* | - |
dc.subject.MESH | Ventricular Dysfunction, Left / mortality | - |
dc.subject.MESH | Ventricular Dysfunction, Left / physiopathology | - |
dc.subject.MESH | Ventricular Dysfunction, Left / therapy | - |
dc.subject.MESH | Ventricular Function, Left | - |
dc.title | Echocardiographic parameters determining cardiovascular outcomes in patients after acute ischemic stroke | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Minkwan Kim | - |
dc.contributor.googleauthor | Hack-Lyoung Kim | - |
dc.contributor.googleauthor | Kyung-Taek Park | - |
dc.contributor.googleauthor | You Nui Kim | - |
dc.contributor.googleauthor | Jae-Sung Lim | - |
dc.contributor.googleauthor | Woo-Hyun Lim | - |
dc.contributor.googleauthor | Jae-Bin Seo | - |
dc.contributor.googleauthor | Sang-Hyun Kim | - |
dc.contributor.googleauthor | Myung-A Kim | - |
dc.contributor.googleauthor | Joo-Hee Zo | - |
dc.identifier.doi | 10.1007/s10554-020-01841-5 | - |
dc.contributor.localId | A05957 | - |
dc.contributor.localId | A01823 | - |
dc.contributor.localId | A03717 | - |
dc.relation.journalcode | J01094 | - |
dc.identifier.eissn | 1875-8312 | - |
dc.identifier.pmid | 32297100 | - |
dc.identifier.url | https://link.springer.com/article/10.1007/s10554-020-01841-5 | - |
dc.subject.keyword | Acute ischemic stroke | - |
dc.subject.keyword | Aortic valve sclerosis | - |
dc.subject.keyword | Left ventricular ejection fraction | - |
dc.subject.keyword | Transthoracic echocardiography | - |
dc.contributor.alternativeName | Kim, Minkwan | - |
dc.contributor.affiliatedAuthor | 김민관 | - |
dc.contributor.affiliatedAuthor | 백순명 | - |
dc.contributor.affiliatedAuthor | 정재호 | - |
dc.citation.volume | 36 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1445 | - |
dc.citation.endPage | 1454 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, Vol.36(8) : 1445-1454, 2020-08 | - |
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