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Asymptomatic patients as a source of COVID-19 infections: A systematic review and meta-analysis
DC Field | Value | Language |
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dc.contributor.author | 신재일 | - |
dc.contributor.author | 이금화 | - |
dc.date.accessioned | 2020-10-05T01:19:58Z | - |
dc.date.available | 2020-10-05T01:19:58Z | - |
dc.date.issued | 2020-09 | - |
dc.identifier.issn | 1201-9712 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/179743 | - |
dc.description.abstract | Background: Coronavirus Disease 2019 (COVID-19) is characterized by an unpredictable disease course, ranging from asymptomatic to severe, life-threatening infections. Asymptomatic COVID-19 infections have been described, and the aim of this systematic review was to summarise their presentation forms. Methods: We searched PubMed® and Google® (1 December 2019 to 29 March 2020) and extracted age, laboratory findings, and computed tomography (CT) scans. Pooled incidence rates of clinical characteristics were analyzed using random-effect models. Results: In total, 506 patients from 34 studies (68 single cases and 438 from case-series) with an asymptomatic course were identified. Patients with normal radiology were younger (19.59 ± 17.17 years) than patients with abnormal radiology (39.14 ± 26.70 years) (p-value = 0.013). Despite being asymptomatic, CT investigations revealed abnormalities in 62.2% of the cases; ground-glass opacities were most frequently observed (43.09% by meta-analysis). Most studies reported normal laboratory findings (61.74% by meta-analysis). Conclusions: More than half of the patients without any symptoms present with CT abnormalities. Asymptomatic patients may be contagious and thus a potential source of transmission of COVID-19. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Asymptomatic patients as a source of COVID-19 infections: A systematic review and meta-analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아청소년과학교실) | - |
dc.contributor.googleauthor | Andreas Kronbichler | - |
dc.contributor.googleauthor | Daniela Kresse | - |
dc.contributor.googleauthor | Sojung Yoon | - |
dc.contributor.googleauthor | Keum Hwa Lee | - |
dc.contributor.googleauthor | Maria Effenberger | - |
dc.contributor.googleauthor | Jae Il Shin | - |
dc.identifier.doi | 10.1016/j.ijid.2020.06.052 | - |
dc.contributor.localId | A02142 | - |
dc.contributor.localId | A04622 | - |
dc.relation.journalcode | J01125 | - |
dc.identifier.eissn | 1878-3511 | - |
dc.identifier.pmid | 32562846 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S1201971220304872 | - |
dc.subject.keyword | Asymptomatic | - |
dc.subject.keyword | Coronavirus disease-19 (COVID-19) | - |
dc.subject.keyword | Meta-analysis | - |
dc.subject.keyword | SARS-CoV-2 | - |
dc.contributor.alternativeName | Shin, Jae Il | - |
dc.contributor.affiliatedAuthor | 신재일 | - |
dc.contributor.affiliatedAuthor | 이금화 | - |
dc.citation.volume | 98 | - |
dc.citation.startPage | 180 | - |
dc.citation.endPage | 186 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, Vol.98 : 180-186, 2020-09 | - |
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