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Serum phosphorus levels are associated with carotid intima-media thickness in asymptomatic postmenopausal women

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dc.contributor.author김종윤-
dc.contributor.author김형수-
dc.contributor.author조시현-
dc.date.accessioned2020-10-05T01:02:12Z-
dc.date.available2020-10-05T01:02:12Z-
dc.date.issued2020-09-
dc.identifier.issn1072-3714-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/179730-
dc.description.abstractObjective: Serum phosphorous is a significant risk factor for increased carotid intima-media thickness. Increased thickness of the carotid intima is a known cause of cardiovascular disease. Coronary heart disease is a significant cause of mortality and morbidity in postmenopausal women. This study aimed to compare the relationship between serum phosphorous concentration and carotid intima-media thickness in healthy asymptomatic postmenopausal women. Methods: A retrospective review of the medical records from a health checkup center in Gangnam Severance hospital between March 2007 and September 2017 was conducted. We examined asymptomatic postmenopausal female patients with age range between 56 and 66 (N = 361) who underwent measurement of carotid intima-media thickness by B-mode ultrasonography. The physiological variables analyzed included mean blood pressure, body mass index, renal function (serum creatinine and estimated glomerular filtration rate), cholesterol levels (total cholesterol, triglyceride, and high- and low-density lipoprotein), serum phosphorous, calcium, electrolytes, diabetic status, hypertension, and albumin. Results: Pearson correlation test showed that carotid intima-media thickness was significantly associated with age (r = 0.192, P < 0.001), mean blood pressure (r = 0.116, P = 0.029), diastolic blood pressure (r = 0.146, P = 0.029), serum phosphorous (r = 0.134, P = 0.012), and lactate dehydrogenase (r = 0.106, P = 0.047). On the basis of age-adjusted multivariate linear regression analysis, carotid intima-media thickness was significantly correlated with serum phosphorous levels (β = 0.273, P = 0.022) in asymptomatic menopausal women. Increased carotid intima-media thickness (cut-off 1.5 mm) was detected, although serum phosphorous was within the normal range (2.8-4.5 mg/dL). Conclusions: Serum phosphorus concentration is significantly associated with carotid intima-media thickness in asymptomatic menopausal women.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherLippincott-Raven Publishers-
dc.relation.isPartOfMENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleSerum phosphorus levels are associated with carotid intima-media thickness in asymptomatic postmenopausal women-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorHyeongsoo Kim-
dc.contributor.googleauthorJeong Sook Kim-
dc.contributor.googleauthorSiHyun Cho-
dc.contributor.googleauthorJong-Youn Kim-
dc.identifier.doi10.1097/GME.0000000000001567-
dc.contributor.localIdA00926-
dc.contributor.localIdA05740-
dc.contributor.localIdA03846-
dc.relation.journalcodeJ02219-
dc.identifier.eissn1530-0374-
dc.identifier.pmid32852457-
dc.contributor.alternativeNameKim, Jong Youn-
dc.contributor.affiliatedAuthor김종윤-
dc.contributor.affiliatedAuthor김형수-
dc.contributor.affiliatedAuthor조시현-
dc.citation.volume27-
dc.citation.number9-
dc.citation.startPage1042-
dc.citation.endPage1046-
dc.identifier.bibliographicCitationMENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, Vol.27(9) : 1042-1046, 2020-09-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers

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