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Sarcopenia in Autoimmune and Rheumatic Diseases: A Comprehensive Review

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dc.contributor.author신재일-
dc.contributor.author이금화-
dc.date.accessioned2020-10-04T16:47:22Z-
dc.date.available2020-10-04T16:47:22Z-
dc.date.issued2020-08-
dc.identifier.issn1661-6596-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/179667-
dc.description.abstractSarcopenia refers to a decrease in skeletal muscle mass and function. Because sarcopenia affects mortality, and causes significant disability, the clinical importance of sarcopenia is emerging. At first, sarcopenia was recognized as an age-related disease but, recently, it has been reported to be prevalent also in younger patients with autoimmune diseases. Specifically, the association of sarcopenia and autoimmune diseases such as rheumatoid arthritis has been studied in detail. Although the pathogenesis of sarcopenia in autoimmune diseases has not been elucidated, chronic inflammation is believed to contribute to sarcopenia, and moreover the pathogenesis seems to be different depending on the respective underlying disease. The definition of sarcopenia differs among studies, which limits direct comparisons. Therefore, in this review, we cover various definitions of sarcopenia used in previous studies and highlight the prevalence of sarcopenia in diverse autoimmune diseases including rheumatoid arthritis, spondyloarthritis, systemic sclerosis, inflammatory bowel disease, and autoimmune diabetes. In addition, we cover the pathogenesis and treatment of sarcopenia in autoimmune and rheumatic diseases. This review provides a comprehensive understanding of sarcopenia in various autoimmune diseases and highlights the need for a consistent definition of sarcopenia.-
dc.description.statementOfResponsibilityopen-
dc.languageINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES-
dc.publisherINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleSarcopenia in Autoimmune and Rheumatic Diseases: A Comprehensive Review-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아청소년과학교실)-
dc.contributor.googleauthorHyo Jin An-
dc.contributor.googleauthorKalthoum Tizaoui-
dc.contributor.googleauthorSalvatore Terrazzino-
dc.contributor.googleauthorSarah Cargnin-
dc.contributor.googleauthorKeum Hwa Lee-
dc.contributor.googleauthorSeoung Wan Nam-
dc.contributor.googleauthorJae Seok Kim-
dc.contributor.googleauthorJae Won Yang-
dc.contributor.googleauthorJun Young Lee-
dc.contributor.googleauthorLee Smith-
dc.contributor.googleauthorAi Koyanagi-
dc.contributor.googleauthorLouis Jacob-
dc.contributor.googleauthorHan Li-
dc.contributor.googleauthorJae Il Shin-
dc.contributor.googleauthorAndreas Kronbichler-
dc.identifier.doi10.3390/ijms21165678-
dc.contributor.localIdA02142-
dc.contributor.localIdA04622-
dc.relation.journalcodeJ01133-
dc.identifier.eissn1422-0067-
dc.identifier.pmid32784808-
dc.subject.keywordautoimmune disease-
dc.subject.keywordinflammatory bowel disease-
dc.subject.keywordrheumatic disease-
dc.subject.keywordrheumatoid arthritis-
dc.subject.keywordsarcopenia-
dc.subject.keywordtype 1 diabetes-
dc.contributor.alternativeNameShin, Jae Il-
dc.contributor.affiliatedAuthor신재일-
dc.contributor.affiliatedAuthor이금화-
dc.citation.volume21-
dc.citation.number16-
dc.citation.startPage5678-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Vol.21(16) : 5678, 2020-08-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

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