Cited 17 times in
Synthesis of 18 F-Labeled Aryl Fluorosulfates via Nucleophilic Radiofluorination
DC Field | Value | Language |
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dc.contributor.author | 유영훈 | - |
dc.contributor.author | 전중현 | - |
dc.date.accessioned | 2020-09-30T16:43:25Z | - |
dc.date.available | 2020-09-30T16:43:25Z | - |
dc.date.issued | 2020-07 | - |
dc.identifier.issn | 1523-7060 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/179593 | - |
dc.description.abstract | Sulfuryl fluoride gas is a key reagent for SO2F transfer. However, conventional SO2F transfer reactions have limited 18F-radiochemistry translation, due to the inaccessibility of gaseous [18F]SO2F2. Herein, we report the first SO2F2-free synthesis of aryl [18F]fluorosulfates from both phenolic and isolated aryl imidazylate precursors with cyclotron-produced 18F-. The radiochemical yields ranged from moderate to good with excellent functional group tolerance. The reliability of our approach was validated by the automated radiosynthesis of 4-acetamidophenyl [18F]fluorosulfate. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | American Chemical Society | - |
dc.relation.isPartOf | ORGANIC LETTERS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Synthesis of 18 F-Labeled Aryl Fluorosulfates via Nucleophilic Radiofluorination | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Nuclear Medicine (핵의학교실) | - |
dc.contributor.googleauthor | Young-Do Kwon | - |
dc.contributor.googleauthor | Min Ho Jeon | - |
dc.contributor.googleauthor | Nam Kyu Park | - |
dc.contributor.googleauthor | Jeong Kon Seo | - |
dc.contributor.googleauthor | Jeongmin Son | - |
dc.contributor.googleauthor | Young Hoon Ryu | - |
dc.contributor.googleauthor | Sung You Hong | - |
dc.contributor.googleauthor | Joong-Hyun Chun | - |
dc.identifier.doi | 10.1021/acs.orglett.0c01868 | - |
dc.contributor.localId | A02485 | - |
dc.contributor.localId | A05406 | - |
dc.relation.journalcode | J03589 | - |
dc.identifier.eissn | 1523-7052 | - |
dc.identifier.pmid | 32589035 | - |
dc.identifier.url | https://pubs.acs.org/doi/10.1021/acs.orglett.0c01868 | - |
dc.contributor.alternativeName | Ryu, Young Hoon | - |
dc.contributor.affiliatedAuthor | 유영훈 | - |
dc.contributor.affiliatedAuthor | 전중현 | - |
dc.citation.volume | 22 | - |
dc.citation.number | 14 | - |
dc.citation.startPage | 5511 | - |
dc.citation.endPage | 5516 | - |
dc.identifier.bibliographicCitation | ORGANIC LETTERS, Vol.22(14) : 5511-5516, 2020-07 | - |
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