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Prospective study of oncologic outcomes after laparoscopic modified complete mesocolic excision for non-metastatic right colon cancer (PIONEER study): study protocol of a multicentre single-arm trial

DC FieldValueLanguage
dc.contributor.author김현기-
dc.contributor.author양승윤-
dc.contributor.author민병소-
dc.contributor.author한윤대-
dc.contributor.author조민수-
dc.date.accessioned2020-09-29T01:42:17Z-
dc.date.available2020-09-29T01:42:17Z-
dc.date.issued2020-07-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/179485-
dc.description.abstractBackground: The introduction of complete mesocolic excision (CME) with central vascular ligation (CVL) for right-sided colon cancer has improved the oncologic outcomes. Recently, we have introduced a modified CME (mCME) procedure that keeps the same principles as the originally described CME but with a more tailored approach. Some retrospective studies have reported the favourable oncologic outcomes of laparoscopic mCME for right-sided colon cancer; however, no prospective multicentre study has yet been conducted. Methods: This study is a multi-institutional, prospective, single-arm study evaluating the oncologic outcomes of laparoscopic mCME for adenocarcinoma arising from the right side of the colon. A total of 250 patients will be recruited from five tertiary referral centres in South Korea. The primary outcome of this study is 3-year disease-free survival. Secondary outcome measures include 3-year overall survival, incidence of surgical complications, completeness of mCME, and distribution of metastatic lymph nodes. The quality of laparoscopic mCME will be assessed on the basis of photographs of the surgical specimen and the operation field after the completion of lymph node dissection. Discussion: This is a prospective multicentre study to evaluate the oncologic outcomes of laparoscopic mCME for right-sided colon cancer. To the best of our knowledge, this will be the first study to prospectively and objectively assess the quality of laparoscopic mCME. The results will provide more evidence about oncologic outcomes with respect to the quality of laparoscopic mCME in right-sided colon cancer. Trial registration: ClinicalTrials.gov ID: NCT03992599 (June 20, 2019). The posted information will be updated as needed to reflect protocol amendments and study progress.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherBioMed Central-
dc.relation.isPartOfBMC CANCER-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleProspective study of oncologic outcomes after laparoscopic modified complete mesocolic excision for non-metastatic right colon cancer (PIONEER study): study protocol of a multicentre single-arm trial-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pathology (병리학교실)-
dc.contributor.googleauthorSeung Yoon Yang-
dc.contributor.googleauthorMin Jung Kim-
dc.contributor.googleauthorBong-Hyeon Kye-
dc.contributor.googleauthorYoon Dae Han-
dc.contributor.googleauthorMin Soo Cho-
dc.contributor.googleauthorSeung-Yong Jeong-
dc.contributor.googleauthorHyeon-Min Cho-
dc.contributor.googleauthorHyunki Kim-
dc.contributor.googleauthorGyeong Hoon Kang-
dc.contributor.googleauthorSeung Ho Song-
dc.contributor.googleauthorJun Seok Park-
dc.contributor.googleauthorJi-Seon Kim-
dc.contributor.googleauthorSoo Yeun Park-
dc.contributor.googleauthorJin Kim-
dc.contributor.googleauthorByung Soh Min-
dc.identifier.doi10.1186/s12885-020-07151-2-
dc.contributor.localIdA01108-
dc.contributor.localIdA05359-
dc.contributor.localIdA05359-
dc.contributor.localIdA01402-
dc.contributor.localIdA01402-
dc.contributor.localIdA04313-
dc.contributor.localIdA04313-
dc.contributor.localIdA03817-
dc.contributor.localIdA03817-
dc.relation.journalcodeJ00351-
dc.identifier.eissn1471-2407-
dc.identifier.pmid32664881-
dc.subject.keywordLaparoscopic surgery-
dc.subject.keywordModified complete mesocolic excision-
dc.subject.keywordOncologic outcomes-
dc.subject.keywordRight-sided colon cancer-
dc.contributor.alternativeNameKim, Hyunki-
dc.contributor.affiliatedAuthor김현기-
dc.contributor.affiliatedAuthor양승윤-
dc.contributor.affiliatedAuthor양승윤-
dc.contributor.affiliatedAuthor민병소-
dc.contributor.affiliatedAuthor민병소-
dc.contributor.affiliatedAuthor한윤대-
dc.contributor.affiliatedAuthor한윤대-
dc.contributor.affiliatedAuthor조민수-
dc.contributor.affiliatedAuthor조민수-
dc.citation.volume20-
dc.citation.number1-
dc.citation.startPage657-
dc.identifier.bibliographicCitationBMC CANCER, Vol.20(1) : 657, 2020-07-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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