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Prediction of postoperative pulmonary complications using preoperative controlling nutritional status (CONUT) score in patients with resectable non-small cell lung cancer

DC Field Value Language
dc.contributor.author이상훈-
dc.contributor.author이상철-
dc.contributor.author김은영-
dc.contributor.author정경수-
dc.contributor.author정지예-
dc.contributor.author장준-
dc.contributor.author백효채-
dc.contributor.author이진구-
dc.contributor.author김대준-
dc.date.accessioned2020-09-29T01:19:17Z-
dc.date.available2020-09-29T01:19:17Z-
dc.date.issued2020-07-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/179471-
dc.description.abstractPostoperative pulmonary complications (PPCs) significantly impact surgical outcome. We investigated the predictive ability of controlling nutritional status (CONUT) for PPC after lung resection in patients with non-small cell lung cancer (NSCLC). We retrospectively reviewed data of 922 patients with NSCLC who underwent complete resection from January 2016-December 2017. We analyzed the frequency and characteristics of PPCs and compared receiver operating characteristic (ROC) curves of various prognostic models to predict PPCs. A CONUT score higher than 1 was considered as a high CONUT score. Total incidence of PPCs was 8.6% (n = 79). The proportion of pneumonia was significantly larger in the high CONUT group (P < 0.05). The CONUT consistently had a higher area under curve (AUC) value (0.64) than other prognostic models (prognostic nutritional index (PNI): AUC = 0.61, Glasgow prognostic score (GPS): AUC = 0.57, and assessment of respiratory risk in surgical patients in Catalonia (ARISCAT): AUC = 0.54). Multivariate analysis identified underweight [Odds ratio (OR) = 4.57, P = 0.002] and high CONUT score (OR = 1.91, P = 0.009) as independent PPCs prognostic factors. One-year mortality rate for high CONUT score was significantly higher (hazard ratio = 7.97; 95% confidence interval, 1.78-35.59). Preoperative CONUT score is an independent predictor of PPCs and 1-year mortality in patients with resectable NSCLC.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherNature Publishing Group-
dc.relation.isPartOfSCIENTIFIC REPORTS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titlePrediction of postoperative pulmonary complications using preoperative controlling nutritional status (CONUT) score in patients with resectable non-small cell lung cancer-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorSang Chul Lee-
dc.contributor.googleauthorJin Gu Lee-
dc.contributor.googleauthorSang Hoon Lee-
dc.contributor.googleauthorEun Young Kim-
dc.contributor.googleauthorJoon Chang-
dc.contributor.googleauthorDae Joon Kim-
dc.contributor.googleauthorHyo Chae Paik-
dc.contributor.googleauthorKyung Young Chung-
dc.contributor.googleauthorJi Ye Jung-
dc.identifier.doi10.1038/s41598-020-68929-9-
dc.contributor.localIdA02836-
dc.contributor.localIdA02831-
dc.contributor.localIdA00811-
dc.contributor.localIdA03570-
dc.contributor.localIdA03735-
dc.contributor.localIdA03472-
dc.contributor.localIdA01846-
dc.contributor.localIdA03225-
dc.contributor.localIdA00368-
dc.relation.journalcodeJ02646-
dc.identifier.eissn2045-2322-
dc.identifier.pmid32709867-
dc.contributor.alternativeNameLee, Sang Hoon-
dc.contributor.affiliatedAuthor이상훈-
dc.contributor.affiliatedAuthor이상철-
dc.contributor.affiliatedAuthor김은영-
dc.contributor.affiliatedAuthor정경수-
dc.contributor.affiliatedAuthor정지예-
dc.contributor.affiliatedAuthor장준-
dc.contributor.affiliatedAuthor백효채-
dc.contributor.affiliatedAuthor이진구-
dc.contributor.affiliatedAuthor김대준-
dc.citation.volume10-
dc.citation.number1-
dc.citation.startPage12385-
dc.identifier.bibliographicCitationSCIENTIFIC REPORTS, Vol.10(1) : 12385, 2020-07-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

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