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Omission of axillary lymph node dissection in patients who underwent total mastectomy with 1 or 2 metastatic lymph nodes
DC Field | Value | Language |
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dc.contributor.author | 박병우 | - |
dc.contributor.author | 정준 | - |
dc.date.accessioned | 2020-09-29T00:44:52Z | - |
dc.date.available | 2020-09-29T00:44:52Z | - |
dc.date.issued | 2020-06 | - |
dc.identifier.issn | 2288-6575 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/179386 | - |
dc.description.abstract | Purpose: Sentinel lymph node biopsy (SLNB) is the standard axillary procedure in early breast cancer patients. In a randomized trial, the survival rates were not different when axillary lymph node dissection (ALND) was omitted in patients with 1 or 2 lymph node metastases who underwent breast conserving surgery. This study aimed to compare the outcomes in patients who underwent total mastectomy (TM) with 1 or 2 metastatic nodes according to the types of axillary surgery. Methods: In total, 79,058 patients registered in the Korean Breast Cancer Society database who underwent TM were included in the analysis. The inclusion criteria were history of TM and SLNB, pathologic T stage 1 or 2, clinically negative axillary lymph nodes, 1 or 2 metastatic axillary lymph nodes, no radiation therapy, and no neoadjuvant therapy. We divided the patients into the SLNB only and SLNB + ALND groups. The groups were matched by propensity scores. We retrospectively analyzed the differences in the overall survival (OS) between the 2 groups. Results: A total of 883 patients were matched in a 1:4 ratio for the SLNB only and SLNB + ALND groups in the cohort from 1999 to 2014. There were no significant differences in OS between the 2 groups (P = 0.413). Subgroup analysis revealed a significant survival benefit in the SLNB + ALND group in the T2 subgroup (P = 0.013). Conclusion: OS did not differ between the 2 groups in early breast cancer patients with 1 or 2 metastatic axillary lymph nodes who underwent TM. Omission of ALND may be considered in selected patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Surgical Society | - |
dc.relation.isPartOf | ANNALS OF SURGICAL TREATMENT AND RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Omission of axillary lymph node dissection in patients who underwent total mastectomy with 1 or 2 metastatic lymph nodes | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Bong Kyun Kim | - |
dc.contributor.googleauthor | Byeong-Woo Park | - |
dc.contributor.googleauthor | Min Hee Hur | - |
dc.contributor.googleauthor | Han-Byoel Lee | - |
dc.contributor.googleauthor | Min Ho Park | - |
dc.contributor.googleauthor | Joon Jeong | - |
dc.contributor.googleauthor | Hyouk Jin Lee | - |
dc.contributor.googleauthor | Jina Lee | - |
dc.contributor.googleauthor | Dongju Kim | - |
dc.contributor.googleauthor | Woo Young Sun | - |
dc.contributor.googleauthor | Korean Breast Cancer Society | - |
dc.identifier.doi | 10.4174/astr.2020.98.6.283 | - |
dc.contributor.localId | A01475 | - |
dc.contributor.localId | A03727 | - |
dc.relation.journalcode | J00180 | - |
dc.identifier.eissn | 2288-6796 | - |
dc.identifier.pmid | 32528907 | - |
dc.subject.keyword | Lymph node dissection | - |
dc.subject.keyword | Mastectomy | - |
dc.subject.keyword | Sentinel lymph node biopsy | - |
dc.subject.keyword | Survival analysis | - |
dc.contributor.alternativeName | Park, Byeong Woo | - |
dc.contributor.affiliatedAuthor | 박병우 | - |
dc.contributor.affiliatedAuthor | 정준 | - |
dc.citation.volume | 98 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 283 | - |
dc.citation.endPage | 290 | - |
dc.identifier.bibliographicCitation | ANNALS OF SURGICAL TREATMENT AND RESEARCH, Vol.98(6) : 283-290, 2020-06 | - |
dc.identifier.rimsid | 67308 | - |
dc.type.rims | ART | - |
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