Cited 9 times in
Association between the Thigh Muscle and Insulin Resistance According to Body Mass Index in Middle-Aged Korean Adults
DC Field | Value | Language |
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dc.contributor.author | 심지선 | - |
dc.contributor.author | 이호규 | - |
dc.contributor.author | 김현창 | - |
dc.date.accessioned | 2020-09-29T00:44:28Z | - |
dc.date.available | 2020-09-29T00:44:28Z | - |
dc.date.issued | 2020-06 | - |
dc.identifier.issn | 2233-6079 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/179384 | - |
dc.description.abstract | Background: We examined the associations between thigh muscle area (TMA) and insulin resistance (IR) according to body mass index (BMI) in middle-aged Korean general population. Methods: TMA was measured using quantitative computed tomography and corrected by body weight (TMA/Wt) in 1,263 men, 788 premenopausal women, and 1,476 postmenopausal women all aged 30 to 64 years. The tertiles of TMA/Wt were calculated separately for men and for premenopausal and postmenopausal women. Homeostatic model assessment for insulin resistance (HOMA-IR) was performed using fasting blood glucose and insulin levels, and increased IR was defined according to sex-specific, top quartiles of HOMA-IR. Associations between the TMA/Wt tertiles and increased IR according to the BMI categories (<25 and ≥25 kg/m²) were assessed using multivariable logistic regression analysis. Results: In men with higher BMIs, but not in those with lower BMIs, the presence of an increased IR had significantly higher odds ratios in the lower TMA/Wt tertiles, even after adjustment for visceral fat area. However, in premenopausal and postmenopausal women, there was no significant inverse association between TMA/Wt tertiles and increased IR, regardless of BMI category. Conclusion: Our findings suggest that the thigh muscle is inversely associated with IR in men, particularly in those with higher BMIs. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Diabetes Association | - |
dc.relation.isPartOf | DIABETES & METABOLISM JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Association between the Thigh Muscle and Insulin Resistance According to Body Mass Index in Middle-Aged Korean Adults | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Preventive Medicine and Public Health (예방의학교실) | - |
dc.contributor.googleauthor | Ji Eun Heo | - |
dc.contributor.googleauthor | Jee Seon Shim | - |
dc.contributor.googleauthor | Hokyou Lee | - |
dc.contributor.googleauthor | Hyeon Chang Kim | - |
dc.identifier.doi | 10.4093/dmj.2019.0110 | - |
dc.contributor.localId | A02212 | - |
dc.contributor.localId | A05838 | - |
dc.contributor.localId | A01142 | - |
dc.relation.journalcode | J00720 | - |
dc.identifier.eissn | 2233-6087 | - |
dc.identifier.pmid | 32431102 | - |
dc.subject.keyword | Body composition | - |
dc.subject.keyword | Insulin resistance | - |
dc.subject.keyword | Muscles | - |
dc.subject.keyword | Sarcopenia | - |
dc.subject.keyword | Tomography, X-ray computed | - |
dc.contributor.alternativeName | Shim, Jee Seon | - |
dc.contributor.affiliatedAuthor | 심지선 | - |
dc.contributor.affiliatedAuthor | 이호규 | - |
dc.contributor.affiliatedAuthor | 김현창 | - |
dc.citation.volume | 44 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 446 | - |
dc.citation.endPage | 457 | - |
dc.identifier.bibliographicCitation | DIABETES & METABOLISM JOURNAL, Vol.44(3) : 446-457, 2020-06 | - |
dc.identifier.rimsid | 67277 | - |
dc.type.rims | ART | - |
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