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HIERARCHICAL MIXED-EFFECTS MODEL FOR HIV DYNAMICS
DC Field | Value | Language |
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dc.contributor.author | 최준용 | - |
dc.date.accessioned | 2020-09-28T11:10:56Z | - |
dc.date.available | 2020-09-28T11:10:56Z | - |
dc.date.issued | 2020-05 | - |
dc.identifier.issn | 0036-1399 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/179184 | - |
dc.description.abstract | A hierarchical mixed-effects model is proposed to account for both individual- and population-level variability in human immunodeficiency virus (HIV) dynamics. This model is implemented by formulating the crucial parameters as random variables in an in-host HIV model. Model reduction is used to guide the choice for a minimal set of parameters, whose distributions are estimated by the global two-stage method. We analyze the system of ordinary differential equations with random coefficients and provide numerical simulations illustrating its asymptotic behaviors. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Society for Industrial and Applied Mathematics | - |
dc.relation.isPartOf | SIAM JOURNAL ON APPLIED MATHEMATICS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | HIERARCHICAL MIXED-EFFECTS MODEL FOR HIV DYNAMICS | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | YUNJEONG LEE | - |
dc.contributor.googleauthor | YOON-GU HWANG | - |
dc.contributor.googleauthor | HEE-DAE KWON | - |
dc.contributor.googleauthor | JUN YONG CHOI | - |
dc.contributor.googleauthor | JEEHYUN LEE | - |
dc.identifier.doi | 10.1137/19M1246031 | - |
dc.contributor.localId | A04191 | - |
dc.relation.journalcode | J03893 | - |
dc.subject.keyword | HIV dynamics | - |
dc.subject.keyword | mixed-effects model | - |
dc.subject.keyword | random ODEs | - |
dc.contributor.alternativeName | Choi, Jun Yong | - |
dc.contributor.affiliatedAuthor | 최준용 | - |
dc.citation.volume | 80 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 1290 | - |
dc.citation.endPage | 1306 | - |
dc.identifier.bibliographicCitation | SIAM JOURNAL ON APPLIED MATHEMATICS, Vol.80(3) : 1290-1306, 2020-05 | - |
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