Cited 14 times in
Review on long-term non-renal complications of childhood nephrotic syndrome
DC Field | Value | Language |
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dc.contributor.author | 신재일 | - |
dc.date.accessioned | 2020-09-28T02:31:52Z | - |
dc.date.available | 2020-09-28T02:31:52Z | - |
dc.date.issued | 2020-03 | - |
dc.identifier.issn | 0803-5253 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/179087 | - |
dc.description.abstract | Background: Nephrotic syndrome (NS) is the most common glomerular childhood disease. A body of literature has described the long-term renal prognosis of childhood-onset idiopathic NS. However, the nonrenal outcomes have not been studied as much. Aim: We aimed to discuss the long-term non-renal outcomes of childhood NS, highlighting studies with a follow-up period of more than 10 years. Results: We reviewed the literature and found that a number of immunosuppressive agents have stopped inflammation, stabilised the podocyte cytoskeleton and reduce proteinuria. However, prolonged treatment has frequently been associated with a high risk of renal and non-renal complications in patients with a complicated disease course, defined as frequent relapses or steroid dependency. Non-renal complications may include impaired longitudinal growth and pubertal development, undesirable fertility outcomes, ocular complications, bone mineral diseases and potential malignancies. Conclusion: This review discusses and summarises the non-renal outcomes of idiopathic childhood NS. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Wiley-Blackwell | - |
dc.relation.isPartOf | ACTA PAEDIATRICA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Review on long-term non-renal complications of childhood nephrotic syndrome | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아청소년과학교실) | - |
dc.contributor.googleauthor | Jiwon M Lee | - |
dc.contributor.googleauthor | Andreas Kronbichler | - |
dc.contributor.googleauthor | Jae Il Shin | - |
dc.contributor.googleauthor | Jun Oh | - |
dc.identifier.doi | 10.1111/apa.15035 | - |
dc.contributor.localId | A02142 | - |
dc.relation.journalcode | J00029 | - |
dc.identifier.eissn | 1651-2227 | - |
dc.identifier.pmid | 31561270 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/abs/10.1111/apa.15035 | - |
dc.subject.keyword | long-term | - |
dc.subject.keyword | morbidity | - |
dc.subject.keyword | nephrotic syndrome | - |
dc.subject.keyword | non-renal complications | - |
dc.subject.keyword | prognosis | - |
dc.subject.keyword | quality of life | - |
dc.contributor.alternativeName | Shin, Jae Il | - |
dc.contributor.affiliatedAuthor | 신재일 | - |
dc.citation.volume | 109 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 460 | - |
dc.citation.endPage | 470 | - |
dc.identifier.bibliographicCitation | ACTA PAEDIATRICA, Vol.109(3) : 460-470, 2020-03 | - |
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