Cited 49 times in
Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians
DC Field | Value | Language |
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dc.contributor.author | 정금지 | - |
dc.contributor.author | 지선하 | - |
dc.date.accessioned | 2020-07-27T16:41:39Z | - |
dc.date.available | 2020-07-27T16:41:39Z | - |
dc.date.issued | 2015-01 | - |
dc.identifier.issn | 0012-1797 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/178457 | - |
dc.description.abstract | Fasting plasma glucose (FPG) has been recognized as an important indicator for the overall glycemic state preceding the onset of metabolic diseases. So far, most indentified genome-wide association loci for FPG were derived from populations with European ancestry, with a few exceptions. To extend a thorough catalog for FPG loci, we conducted meta-analyses of 13 genome-wide association studies in up to 24,740 nondiabetic subjects with East Asian ancestry. Follow-up replication analyses in up to an additional 21,345 participants identified three new FPG loci reaching genome-wide significance in or near PDK1-RAPGEF4, KANK1, and IGF1R. Our results could provide additional insight into the genetic variation implicated in fasting glucose regulation. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | American Diabetes Association | - |
dc.relation.isPartOf | DIABETES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Asian Continental Ancestry Group / genetics* | - |
dc.subject.MESH | Blood Glucose / genetics* | - |
dc.subject.MESH | Blood Glucose / metabolism* | - |
dc.subject.MESH | Far East | - |
dc.subject.MESH | Fasting | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Genetic Variation | - |
dc.subject.MESH | Genome-Wide Association Study* | - |
dc.subject.MESH | Genotype | - |
dc.subject.MESH | Guanine Nucleotide Exchange Factors / genetics | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Phenotype | - |
dc.subject.MESH | Protein-Serine-Threonine Kinases / genetics | - |
dc.subject.MESH | Pyruvate Dehydrogenase (Acetyl-Transferring) Kinase | - |
dc.subject.MESH | Receptor, IGF Type 1 / genetics | - |
dc.subject.MESH | Tumor Suppressor Proteins / genetics | - |
dc.title | Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians | - |
dc.type | Article | - |
dc.contributor.college | Graduate School of Public Health (보건대학원) | - |
dc.contributor.department | Graduate School of Public Health (보건대학원) | - |
dc.contributor.googleauthor | Joo-Yeon Hwang | - |
dc.contributor.googleauthor | Xueling Sim | - |
dc.contributor.googleauthor | Ying Wu | - |
dc.contributor.googleauthor | Jun Liang | - |
dc.contributor.googleauthor | Yasuharu Tabara | - |
dc.contributor.googleauthor | Cheng Hu | - |
dc.contributor.googleauthor | Kazuo Hara | - |
dc.contributor.googleauthor | Claudia H T Tam | - |
dc.contributor.googleauthor | Qiuyin Cai | - |
dc.contributor.googleauthor | Qi Zhao | - |
dc.contributor.googleauthor | Sunha Jee | - |
dc.contributor.googleauthor | Fumihiko Takeuchi | - |
dc.contributor.googleauthor | Min Jin Go | - |
dc.contributor.googleauthor | Rick Twee Hee Ong | - |
dc.contributor.googleauthor | Takayoshi Ohkubo | - |
dc.contributor.googleauthor | Young Jin Kim | - |
dc.contributor.googleauthor | Rong Zhang | - |
dc.contributor.googleauthor | Toshimasa Yamauchi | - |
dc.contributor.googleauthor | Wing Yee So | - |
dc.contributor.googleauthor | Jirong Long | - |
dc.contributor.googleauthor | Dongfeng Gu | - |
dc.contributor.googleauthor | Nanette R Lee | - |
dc.contributor.googleauthor | Soriul Kim | - |
dc.contributor.googleauthor | Tomohiro Katsuya | - |
dc.contributor.googleauthor | Ji Hee Oh | - |
dc.contributor.googleauthor | Jianjun Liu | - |
dc.contributor.googleauthor | Satoshi Umemura | - |
dc.contributor.googleauthor | Yeon-Jung Kim | - |
dc.contributor.googleauthor | Feng Jiang | - |
dc.contributor.googleauthor | Shiro Maeda | - |
dc.contributor.googleauthor | Juliana C N Chan | - |
dc.contributor.googleauthor | Wei Lu | - |
dc.contributor.googleauthor | James E Hixson | - |
dc.contributor.googleauthor | Linda S Adair | - |
dc.contributor.googleauthor | Keum Ji Jung | - |
dc.contributor.googleauthor | Toru Nabika | - |
dc.contributor.googleauthor | Jae-Bum Bae | - |
dc.contributor.googleauthor | Mi Hee Lee | - |
dc.contributor.googleauthor | Mark Seielstad | - |
dc.contributor.googleauthor | Terri L Young | - |
dc.contributor.googleauthor | Yik Ying Teo | - |
dc.contributor.googleauthor | Yoshikuni Kita | - |
dc.contributor.googleauthor | Naoyuki Takashima | - |
dc.contributor.googleauthor | Haruhiko Osawa | - |
dc.contributor.googleauthor | So-Hyun Lee | - |
dc.contributor.googleauthor | Min-Ho Shin | - |
dc.contributor.googleauthor | Dong Hoon Shin | - |
dc.contributor.googleauthor | Bo Youl Choi | - |
dc.contributor.googleauthor | Jiajun Shi | - |
dc.contributor.googleauthor | Yu-Tang Gao | - |
dc.contributor.googleauthor | Yong-Bing Xiang | - |
dc.contributor.googleauthor | Wei Zheng | - |
dc.contributor.googleauthor | Norihiro Kato | - |
dc.contributor.googleauthor | Miwuk Yoon | - |
dc.contributor.googleauthor | Jiang He | - |
dc.contributor.googleauthor | Xiao Ou Shu | - |
dc.contributor.googleauthor | Ronald C W Ma | - |
dc.contributor.googleauthor | Takashi Kadowaki | - |
dc.contributor.googleauthor | Weiping Jia | - |
dc.contributor.googleauthor | Tetsuro Miki | - |
dc.contributor.googleauthor | Lu Qi | - |
dc.contributor.googleauthor | E Shyong Tai | - |
dc.contributor.googleauthor | Karen L Mohlke | - |
dc.contributor.googleauthor | Bok-Ghee Han | - |
dc.contributor.googleauthor | Yoon Shin Cho | - |
dc.contributor.googleauthor | Bong-Jo Kim | - |
dc.identifier.doi | 10.2337/db14-0563 | - |
dc.contributor.localId | A03580 | - |
dc.contributor.localId | A03965 | - |
dc.relation.journalcode | J00718 | - |
dc.identifier.eissn | 1939-327X | - |
dc.identifier.pmid | 25187374 | - |
dc.contributor.alternativeName | Jung, Keum Ji | - |
dc.contributor.affiliatedAuthor | 정금지 | - |
dc.contributor.affiliatedAuthor | 지선하 | - |
dc.citation.volume | 64 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 291 | - |
dc.citation.endPage | 298 | - |
dc.identifier.bibliographicCitation | DIABETES, Vol.64(1) : 291-298, 2015-01 | - |
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