YUHSpace

BROWSE

Export
257 365

Cited 46 times in

Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians

DC Field Value Language
dc.contributor.author정금지-
dc.contributor.author지선하-
dc.date.accessioned2020-07-27T16:41:39Z-
dc.date.available2020-07-27T16:41:39Z-
dc.date.issued2015-01-
dc.identifier.issn0012-1797-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/178457-
dc.description.abstractFasting plasma glucose (FPG) has been recognized as an important indicator for the overall glycemic state preceding the onset of metabolic diseases. So far, most indentified genome-wide association loci for FPG were derived from populations with European ancestry, with a few exceptions. To extend a thorough catalog for FPG loci, we conducted meta-analyses of 13 genome-wide association studies in up to 24,740 nondiabetic subjects with East Asian ancestry. Follow-up replication analyses in up to an additional 21,345 participants identified three new FPG loci reaching genome-wide significance in or near PDK1-RAPGEF4, KANK1, and IGF1R. Our results could provide additional insight into the genetic variation implicated in fasting glucose regulation.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherAmerican Diabetes Association-
dc.relation.isPartOfDIABETES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAsian Continental Ancestry Group / genetics*-
dc.subject.MESHBlood Glucose / genetics*-
dc.subject.MESHBlood Glucose / metabolism*-
dc.subject.MESHFar East-
dc.subject.MESHFasting-
dc.subject.MESHFemale-
dc.subject.MESHGenetic Variation-
dc.subject.MESHGenome-Wide Association Study*-
dc.subject.MESHGenotype-
dc.subject.MESHGuanine Nucleotide Exchange Factors / genetics-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPhenotype-
dc.subject.MESHProtein-Serine-Threonine Kinases / genetics-
dc.subject.MESHPyruvate Dehydrogenase (Acetyl-Transferring) Kinase-
dc.subject.MESHReceptor, IGF Type 1 / genetics-
dc.subject.MESHTumor Suppressor Proteins / genetics-
dc.titleGenome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians-
dc.typeArticle-
dc.contributor.collegeGraduate School of Public Health (보건대학원)-
dc.contributor.departmentGraduate School of Public Health (보건대학원)-
dc.contributor.googleauthorJoo-Yeon Hwang-
dc.contributor.googleauthorXueling Sim-
dc.contributor.googleauthorYing Wu-
dc.contributor.googleauthorJun Liang-
dc.contributor.googleauthorYasuharu Tabara-
dc.contributor.googleauthorCheng Hu-
dc.contributor.googleauthorKazuo Hara-
dc.contributor.googleauthorClaudia H T Tam-
dc.contributor.googleauthorQiuyin Cai-
dc.contributor.googleauthorQi Zhao-
dc.contributor.googleauthorSunha Jee-
dc.contributor.googleauthorFumihiko Takeuchi-
dc.contributor.googleauthorMin Jin Go-
dc.contributor.googleauthorRick Twee Hee Ong-
dc.contributor.googleauthorTakayoshi Ohkubo-
dc.contributor.googleauthorYoung Jin Kim-
dc.contributor.googleauthorRong Zhang-
dc.contributor.googleauthorToshimasa Yamauchi-
dc.contributor.googleauthorWing Yee So-
dc.contributor.googleauthorJirong Long-
dc.contributor.googleauthorDongfeng Gu-
dc.contributor.googleauthorNanette R Lee-
dc.contributor.googleauthorSoriul Kim-
dc.contributor.googleauthorTomohiro Katsuya-
dc.contributor.googleauthorJi Hee Oh-
dc.contributor.googleauthorJianjun Liu-
dc.contributor.googleauthorSatoshi Umemura-
dc.contributor.googleauthorYeon-Jung Kim-
dc.contributor.googleauthorFeng Jiang-
dc.contributor.googleauthorShiro Maeda-
dc.contributor.googleauthorJuliana C N Chan-
dc.contributor.googleauthorWei Lu-
dc.contributor.googleauthorJames E Hixson-
dc.contributor.googleauthorLinda S Adair-
dc.contributor.googleauthorKeum Ji Jung-
dc.contributor.googleauthorToru Nabika-
dc.contributor.googleauthorJae-Bum Bae-
dc.contributor.googleauthorMi Hee Lee-
dc.contributor.googleauthorMark Seielstad-
dc.contributor.googleauthorTerri L Young-
dc.contributor.googleauthorYik Ying Teo-
dc.contributor.googleauthorYoshikuni Kita-
dc.contributor.googleauthorNaoyuki Takashima-
dc.contributor.googleauthorHaruhiko Osawa-
dc.contributor.googleauthorSo-Hyun Lee-
dc.contributor.googleauthorMin-Ho Shin-
dc.contributor.googleauthorDong Hoon Shin-
dc.contributor.googleauthorBo Youl Choi-
dc.contributor.googleauthorJiajun Shi-
dc.contributor.googleauthorYu-Tang Gao-
dc.contributor.googleauthorYong-Bing Xiang-
dc.contributor.googleauthorWei Zheng-
dc.contributor.googleauthorNorihiro Kato-
dc.contributor.googleauthorMiwuk Yoon-
dc.contributor.googleauthorJiang He-
dc.contributor.googleauthorXiao Ou Shu-
dc.contributor.googleauthorRonald C W Ma-
dc.contributor.googleauthorTakashi Kadowaki-
dc.contributor.googleauthorWeiping Jia-
dc.contributor.googleauthorTetsuro Miki-
dc.contributor.googleauthorLu Qi-
dc.contributor.googleauthorE Shyong Tai-
dc.contributor.googleauthorKaren L Mohlke-
dc.contributor.googleauthorBok-Ghee Han-
dc.contributor.googleauthorYoon Shin Cho-
dc.contributor.googleauthorBong-Jo Kim-
dc.identifier.doi10.2337/db14-0563-
dc.contributor.localIdA03580-
dc.contributor.localIdA03965-
dc.relation.journalcodeJ00718-
dc.identifier.eissn1939-327X-
dc.identifier.pmid25187374-
dc.contributor.alternativeNameJung, Keum Ji-
dc.contributor.affiliatedAuthor정금지-
dc.contributor.affiliatedAuthor지선하-
dc.citation.volume64-
dc.citation.number1-
dc.citation.startPage291-
dc.citation.endPage298-
dc.identifier.bibliographicCitationDIABETES, Vol.64(1) : 291-298, 2015-01-
Appears in Collections:
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers
Show simple item record Find it @ YMLIB

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

  • License
    sherpa_romeo
    sherpa_juliet

OAK

DSpace Software Copyright © 2002-2017 Duraspace Yonsei University Medical Library All right Reserves. / TEL:02-2228-2915 /
YUHSpace는 국립중앙도서관 OAK 보급사업으로 구축되었습니다.

Browse

Links