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Generation of an Induced Pluripotent Stem Cell (iPSC) Line From a 42-year-old Adult Cerebral Type X-linked Adrenoleukodystrophy (X-ALD) Patient

DC FieldValueLanguage
dc.contributor.author강훈철-
dc.date.accessioned2020-07-09T16:40:29Z-
dc.date.available2020-07-09T16:40:29Z-
dc.date.issued2019-04-
dc.identifier.issn1873-5061-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/178101-
dc.description.abstractX-linked Adrenoleukodystrophy (X-ALD) is a neuro-metabolic disorder that is caused by malfunction of a peroxisomal transporter protein, adenosine ATP-binding cassette transporter superfamily D member 1 (ABCD1). We established an induced pluripotent stem cell (iPSC) line from a 42-year-old male X-ALD patient-derived dermal fibroblasts with Sendai virus-mediated reprogramming. Established iPSCs stably expanded, expressed genes of pluripotency, and maintained normal karyotype. In vitro differentiation assay revealed the characteristics of all three germ layers.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherElsevier-
dc.relation.isPartOfSTEM CELL RESEARCH-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHATP Binding Cassette Transporter, Subfamily D, Member 1 / genetics*-
dc.subject.MESHAdrenoleukodystrophy / genetics*-
dc.subject.MESHAdult-
dc.subject.MESHCell Differentiation-
dc.subject.MESHCell Line*-
dc.subject.MESHCellular Reprogramming Techniques-
dc.subject.MESHHumans-
dc.subject.MESHINDEL Mutation-
dc.subject.MESHInduced Pluripotent Stem Cells*-
dc.subject.MESHKaryotype-
dc.subject.MESHMale-
dc.titleGeneration of an Induced Pluripotent Stem Cell (iPSC) Line From a 42-year-old Adult Cerebral Type X-linked Adrenoleukodystrophy (X-ALD) Patient-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아청소년과학교실)-
dc.contributor.googleauthorGyu-Bum Yeon-
dc.contributor.googleauthorDaryeon Son-
dc.contributor.googleauthorPhil Jun Kang-
dc.contributor.googleauthorSeung-Min Oh-
dc.contributor.googleauthorHun Lim-
dc.contributor.googleauthorHoon-Chul Kang-
dc.contributor.googleauthorSeungkwon You-
dc.contributor.googleauthorDae-Sung Kim-
dc.identifier.doi10.1016/j.scr.2019.101425-
dc.contributor.localIdA00102-
dc.relation.journalcodeJ02680-
dc.identifier.eissn1876-7753-
dc.identifier.pmid30921588-
dc.contributor.alternativeNameKang, Hoon Chul-
dc.contributor.affiliatedAuthor강훈철-
dc.citation.volume36-
dc.citation.startPagee101425-
dc.identifier.bibliographicCitationSTEM CELL RESEARCH, Vol.36 : e101425, 2019-04-
dc.identifier.rimsid64417-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

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