Cited 2 times in
Generation of an Induced Pluripotent Stem Cell (iPSC) Line From a 42-year-old Adult Cerebral Type X-linked Adrenoleukodystrophy (X-ALD) Patient
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강훈철 | - |
dc.date.accessioned | 2020-07-09T16:40:29Z | - |
dc.date.available | 2020-07-09T16:40:29Z | - |
dc.date.issued | 2019-04 | - |
dc.identifier.issn | 1873-5061 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/178101 | - |
dc.description.abstract | X-linked Adrenoleukodystrophy (X-ALD) is a neuro-metabolic disorder that is caused by malfunction of a peroxisomal transporter protein, adenosine ATP-binding cassette transporter superfamily D member 1 (ABCD1). We established an induced pluripotent stem cell (iPSC) line from a 42-year-old male X-ALD patient-derived dermal fibroblasts with Sendai virus-mediated reprogramming. Established iPSCs stably expanded, expressed genes of pluripotency, and maintained normal karyotype. In vitro differentiation assay revealed the characteristics of all three germ layers. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | STEM CELL RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | ATP Binding Cassette Transporter, Subfamily D, Member 1 / genetics* | - |
dc.subject.MESH | Adrenoleukodystrophy / genetics* | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Cell Differentiation | - |
dc.subject.MESH | Cell Line* | - |
dc.subject.MESH | Cellular Reprogramming Techniques | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | INDEL Mutation | - |
dc.subject.MESH | Induced Pluripotent Stem Cells* | - |
dc.subject.MESH | Karyotype | - |
dc.subject.MESH | Male | - |
dc.title | Generation of an Induced Pluripotent Stem Cell (iPSC) Line From a 42-year-old Adult Cerebral Type X-linked Adrenoleukodystrophy (X-ALD) Patient | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아청소년과학교실) | - |
dc.contributor.googleauthor | Gyu-Bum Yeon | - |
dc.contributor.googleauthor | Daryeon Son | - |
dc.contributor.googleauthor | Phil Jun Kang | - |
dc.contributor.googleauthor | Seung-Min Oh | - |
dc.contributor.googleauthor | Hun Lim | - |
dc.contributor.googleauthor | Hoon-Chul Kang | - |
dc.contributor.googleauthor | Seungkwon You | - |
dc.contributor.googleauthor | Dae-Sung Kim | - |
dc.identifier.doi | 10.1016/j.scr.2019.101425 | - |
dc.contributor.localId | A00102 | - |
dc.relation.journalcode | J02680 | - |
dc.identifier.eissn | 1876-7753 | - |
dc.identifier.pmid | 30921588 | - |
dc.contributor.alternativeName | Kang, Hoon Chul | - |
dc.contributor.affiliatedAuthor | 강훈철 | - |
dc.citation.volume | 36 | - |
dc.citation.startPage | e101425 | - |
dc.identifier.bibliographicCitation | STEM CELL RESEARCH, Vol.36 : e101425, 2019-04 | - |
dc.identifier.rimsid | 64417 | - |
dc.type.rims | ART | - |
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