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위암 환자에서 혈청 CA72-4의 진단적 의의
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정재복 | - |
dc.date.accessioned | 2020-07-03T17:37:28Z | - |
dc.date.available | 2020-07-03T17:37:28Z | - |
dc.date.issued | 1997 | - |
dc.identifier.issn | 1598-9992 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/177701 | - |
dc.description.abstract | Background/Aims: The serum tumor markers, such as CEA and CA19-9, for gastric cancer have been used but their positive rates are not high. In this study the value of a new serum marker, CA72-4, was compared with the serum activities of CEA and CA19-9 in a consecutive series of patients with gastric cancer. Methods: Fifty-three patients(35 men and 18 women; mean age, 60 years) with histologically diagnosed adenocarcinoma of the stomach, were evaluated. Serum TAG-72 antigen was determined by a double determinant radioimmunometric assay kit, CA72-4, and serum CEA and CA19-9 levels were also measured. Results: CA72-4 had a very high specificity(100%) for benign gastric disease. In gastric carcinoma, the positive rate of CA72-4 was 28% and was not so different to that of CA19-9, 34%, and CEA, 32%. There was significantly increased positive rates of CA72-4, CA19-9 and CEA in patients with advanced gastric cancer than those with early gastric cancer(p<0.01) but no significant difference in CA72-4, CA19-9 and CEA. There was no significant difference in positive rates of CA72-4, CA19-9 and CEA in patients with distant metastases or lymph node metastases than those without metastases. The positive rates of combined use of serum CA72-4 and CA19-9, CA72-4 and CEA, and CA72-4, CA19-9 and CEA were 43%, 45% and 51%. Conclusions: The results of this study suggest that CA72-4 is not better in the serodiagnosis of gastric cancer than conventional tumor markers, CA19-9 and CEA. However, despite considerable numbers of advanced gastric cancer patients with positive CA72-4, there is little clinical significance of CA72-4 in the serodiagnosis of gastric cancer. (Korean J Gastroenterol 1997; 29:9 - 16) | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean Journal of Gastroenterology | - |
dc.publisher | Korean Journal of Gastroenterology | - |
dc.relation.isPartOf | Korean Journal of Gastroenterology | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 위암 환자에서 혈청 CA72-4의 진단적 의의 | - |
dc.title.alternative | The Diagnostic Significance of CA72-4 in Gastric Cancer Patient | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | 이세준 | - |
dc.contributor.googleauthor | 정재복 | - |
dc.contributor.googleauthor | 신현승 | - |
dc.contributor.googleauthor | 송시영 | - |
dc.contributor.googleauthor | 강진경 | - |
dc.contributor.googleauthor | 박인서 | - |
dc.contributor.localId | A03706 | - |
dc.relation.journalcode | J02015 | - |
dc.identifier.eissn | 2233-6869 | - |
dc.contributor.alternativeName | Chung, Jae Bock | - |
dc.contributor.affiliatedAuthor | 정재복 | - |
dc.citation.volume | 29 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 9 | - |
dc.citation.endPage | 16 | - |
dc.identifier.bibliographicCitation | Korean Journal of Gastroenterology, Vol.29(1) : 9-16, 1997 | - |
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