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Efficacy of a topical agent SS-cream in the treatment of premature ejaculation: preliminary clinical studies
DC Field | Value | Language |
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dc.contributor.author | 최영득 | - |
dc.date.accessioned | 2020-07-03T17:20:32Z | - |
dc.date.available | 2020-07-03T17:20:32Z | - |
dc.date.issued | 1997 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/177455 | - |
dc.description.abstract | SS-cream is a topical agent for treating premature ejaculation (PE) which is made with extracts from 9 natural products. We evaluated the efficacy of SS-cream in the treatment of PE. An open pilot study was performed in 186 patients with PE. The mean ejaculatory latency from intromission to ejaculation was 1.5 minutes. Sixty-four of the 186 patients (34.4%) were combined with mild erectile dysfunction in whom penile rigidity was not sufficient to be satisfied in sexual activity. Patients were instructed to apply 0.1 gm. of SS-cream on the glans penis 1 hour before sexual contact and to wash out the cream before sexual intromission. Patients were asked to complete a report form including ejaculatory latency, the degree of satisfaction in the sexual lives of both themselves and their partners, and any adverse effects after each application. One hundred and sixty-six out of 186 patients (89.2%) reported they were satisfied with the application of the SS-cream and the mean ejaculatory latency was significantly prolonged to 10.89 +/- 5.60 minutes. The mean ejaculatory latency was 9.85 +/- 3.58 minutes in 52 out of 64 patients (81.2%) with mild erectile dysfunction. There was no significant difference in the changes of ejaculatory latencies between patients with pure PE and patients with mild erectile dysfunction. Twenty patients (10.8%) claimed to have no changes of ejaculatory latencies after the application of SS-cream. Adverse effects were noted in 11 patients (5.9%), which were mild local irritation symptoms in 7 patients, and delayed ejaculation of more than 30 minutes in 4 patients, the symptoms subsided spontaneously within 4 hours. These results indicate SS-cream is effective in the treatment of PE and also PE combined with mild erectile dysfunction with a few side effects. Further studies on the action mechanisms of SS-cream and a double blind placebo-controlled trial are needed. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Yonsei University | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Administration, Topical | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Drugs, Chinese Herbal/administration & dosage* | - |
dc.subject.MESH | Ejaculation/drug effects* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Penile Erection/drug effects | - |
dc.title | Efficacy of a topical agent SS-cream in the treatment of premature ejaculation: preliminary clinical studies | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨의학교실) | - |
dc.contributor.googleauthor | Zhong Cheng Xin | - |
dc.contributor.googleauthor | Young Deuk Choi | - |
dc.contributor.googleauthor | Soo Hyung Lee | - |
dc.contributor.googleauthor | Hyung Ki Choi | - |
dc.identifier.doi | 10.3349/ymj.1997.38.2.91 | - |
dc.contributor.localId | A04111 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 9175486 | - |
dc.contributor.alternativeName | Choi, Young Deuk | - |
dc.contributor.affiliatedAuthor | 최영득 | - |
dc.citation.volume | 38 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 91 | - |
dc.citation.endPage | 95 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.38(2) : 91-95, 1997 | - |
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