Cited 3 times in
Activity-dependent conduction velocity changes of A(delta) fibers in a rat model of neuropathy
DC Field | Value | Language |
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dc.contributor.author | 임중우 | - |
dc.date.accessioned | 2020-07-03T17:15:32Z | - |
dc.date.available | 2020-07-03T17:15:32Z | - |
dc.date.issued | 1997 | - |
dc.identifier.issn | 0959-4965 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/177386 | - |
dc.description.abstract | Activity-dependent changes of conduction velocity (CV) and conduction block in single A(delta) fibers of primary afferent neurons were characterized in a rat model of neuropathy (NP). Injured dorsal root (DR) fiber in NP rats exhibited profoundly greater decreases of CV following impulse activity than did DR fiber in normal rats. Activity-dependent conduction block was absent up to 100 Hz of activity rate in DR fiber of NP rats, but was present above 25 Hz in normal rats. Profiles of activity dependence in sciatic fibers were similar in both NP and normal rats. These results suggest that nerve injury may alter activity-dependent hypoexcitability of A(delta) DR fibers. Furthermore, this excitability change may be responsible for the elevated pain perception in neuropathy. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | NEUROREPORT | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Ganglia, Spinal/pathology | - |
dc.subject.MESH | Ganglia, Spinal/physiopathology | - |
dc.subject.MESH | Models, Neurological | - |
dc.subject.MESH | Nerve Fibers, Myelinated/physiology* | - |
dc.subject.MESH | Neural Conduction/physiology* | - |
dc.subject.MESH | Peripheral Nerve Injuries | - |
dc.subject.MESH | Peripheral Nerves/physiopathology* | - |
dc.subject.MESH | Rats | - |
dc.subject.MESH | Rats, Sprague-Dawley | - |
dc.subject.MESH | Sciatic Nerve/injuries | - |
dc.subject.MESH | Sciatic Nerve/physiopathology | - |
dc.title | Activity-dependent conduction velocity changes of A(delta) fibers in a rat model of neuropathy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Physiology (생리학교실) | - |
dc.contributor.googleauthor | Won CK | - |
dc.contributor.googleauthor | Oh SJ | - |
dc.contributor.googleauthor | Jung SC | - |
dc.contributor.googleauthor | Choi YR | - |
dc.contributor.googleauthor | Kim YI | - |
dc.contributor.googleauthor | Leem JW | - |
dc.contributor.googleauthor | Shin HC | - |
dc.identifier.doi | 10.1097/00001756-199710200-00004 | - |
dc.contributor.localId | A03409 | - |
dc.relation.journalcode | J02361 | - |
dc.identifier.eissn | 1473-558X | - |
dc.identifier.pmid | 9351643 | - |
dc.identifier.url | https://insights.ovid.com/crossref?an=00001756-199710200-00004 | - |
dc.contributor.alternativeName | Leem, Joong Woo | - |
dc.contributor.affiliatedAuthor | 임중우 | - |
dc.citation.volume | 8 | - |
dc.citation.number | 15 | - |
dc.citation.startPage | 3201 | - |
dc.citation.endPage | 3205 | - |
dc.identifier.bibliographicCitation | NEUROREPORT, Vol.8(15) : 3201-3205, 1997 | - |
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