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Effects of Repeated Short versus Single Long Episodes of Focal Ischemia on Somatosensory Evoked Potentials and Development of Cerebral Infarction in Cats

DC FieldValueLanguage
dc.contributor.author주진양-
dc.date.accessioned2020-07-03T17:15:19Z-
dc.date.available2020-07-03T17:15:19Z-
dc.date.issued1997-
dc.identifier.issn0470-8105-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/177384-
dc.description.abstractThe effects of repeated short episodes of focal ischemia at 30-minute intervals or a single equivalent long episode of focal ischemia on neuronal function and development of cerebral infarction were compared using somatosensory evoked potential (SEP) recording and 2,3,5-triphenyltetrazolium chloride staining in a cat model. Seventeen cats underwent transorbital occlusion of the middle cerebral artery (MCA), using one of three procedures: sham-operation; single 1-hour occlusion of the MCA, followed by 3 hours of recirculation; or three 20-minute occlusions of the MCA at 30-minute intervals, followed by 3 hours of recirculation. Two of six cats in the single long-term occlusion group showed recovery of SEP, whereas all six cats in the repeated short-term occlusion group showed recovery of SEP at 3 hours after recirculation. All six cats in the single long-term occlusion group had cerebral infarction of various sizes, but only one cat in the repeated short-term occlusion group developed infarction. Repeated short episodes of focal ischemia are relatively less damaging than a single equivalent long episode of focal ischemia, even if the reperfusion interval is extended to 30 minutes.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish, Japanese-
dc.publisherJapan Neurosurgical Society-
dc.relation.isPartOfNEUROLOGIA MEDICO-CHIRURGICA-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAnimals-
dc.subject.MESHBrain Ischemia/pathology-
dc.subject.MESHBrain Ischemia/physiopathology*-
dc.subject.MESHCats-
dc.subject.MESHCerebral Infarction/pathology-
dc.subject.MESHCerebral Infarction/physiopathology*-
dc.subject.MESHDisease Models, Animal-
dc.subject.MESHEvoked Potentials, Somatosensory/physiology*-
dc.subject.MESHTime Factors-
dc.titleEffects of Repeated Short versus Single Long Episodes of Focal Ischemia on Somatosensory Evoked Potentials and Development of Cerebral Infarction in Cats-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurosurgery (신경외과학교실)-
dc.contributor.googleauthorKyu Chang LEE-
dc.contributor.googleauthorJin Yang JOO-
dc.contributor.googleauthorSeung Kon HUH-
dc.contributor.googleauthorTai Seung KIM-
dc.identifier.doi10.2176/nmc.37.447-
dc.contributor.localIdA03959-
dc.relation.journalcodeJ02336-
dc.identifier.eissn1349-8029-
dc.identifier.pmid9232095-
dc.contributor.alternativeNameJoo, Jin Yang-
dc.contributor.affiliatedAuthor주진양-
dc.citation.volume37-
dc.citation.number6-
dc.citation.startPage447-
dc.citation.endPage452-
dc.identifier.bibliographicCitationNEUROLOGIA MEDICO-CHIRURGICA, Vol.37(6) : 447-452, 1997-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers

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