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보조 생식술 결과에 있어서 기저혈중 Inhibin-B의 예후인자로서의 유용성

DC Field Value Language
dc.contributor.author배상욱-
dc.contributor.author이병석-
dc.date.accessioned2020-07-03T17:13:29Z-
dc.date.available2020-07-03T17:13:29Z-
dc.date.issued1997-
dc.identifier.issn1226-2951-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/177361-
dc.description.abstractThis study was performed to determine if women with day 3 serum inhibin-B concentrations <45pg/ml (conversion factor to SI unit, 1.00) demonstrate a pro. response to ovulation induction and assisted reproductive technology outcome to women with inhibin-B > or = 45pg/ml, independant of day 3 FSH, E2 and patient age. From Jan 1996 to Dec 1996, 16 volunteers patients who underwent 25 IVF cycles with luteal phase GnRH agonist suppression and HMG stimulation were allocated to the study group. We evaluated day 3 serum inhibits-B, FSH, E2, peak E2, cancellation rate per initiated cycle (%) and clinical pregnancy rate per initiated cycle (%) according to the above two groups and independent of patient age, day 3 FSH, day 3 E2 and all of above combined. Women with day 3 serum inhibin-B > or =45pg/m1 demonstrated higher average day 3 inhibits-B level, clinical pregnancy rate per initiated cycle (20.3+/-2.5 pg/ml vs 80.9+/- 5.0pg/ml, p<0.05; 24.8% vs 8.5%, p<0.05) and lower day 3 FSH level, cancellation rate per initiated cycle (6.9+/-0.3 mIU/ml vs 8.5+/-0.5 mIU/ml, p<0.05; 1.5% vs 9.0%, p<0.05). Women with day 3 serum inhibin> or =45pg/ml and age<40 year demonstrated higher pregnancy rate per initiated cycle (28.2% vs 7.4%, p<0.05) and lows. day 3 FSH level, cancellation rate per initiated cycle (6.9+/-0.5 mIU/ml vs 8.2+/-0.7 mIU/ml, p<0.05; 1.0% vs 9.0%, p<0.05). Women with day 3 serum inhibin> or =45pg/ml and day 3 FSH<15mIU/inl demonstrated higher pregnancy rate per initiated cycle (33.5% vs 9.5%, p<0.05) and lower day 3 FSH level, cancellation rate per initiated cycle (7.7+/- 0.2 mIU/ml vs 8.5+/-0.5 mIU/ml, p<0.05; 1.5% vs 10.0%, p<0.05). Women with day 3 serum inhibin> or =45pg/ml and day 3 E2<50pq/ml demonstrated higher pregnancy rate per initiated cycle (30.0% vs 9.5%, p<0.05) and lower cancellation rate per initiated cycle (1.5% vs 9.5%, p<0.05). Women with day 3 serum inhibin> or =45pg/ml, age<40 year, day 3 FSH<15mIU/ml and day 3 E2<50pg/m1 demonstrated higher pregnancy rate per initiated cycle (30.0% vs 10.8%, p<0.05) and lower day 3 FSH level, cancellation rate per initiated cycle (6.8+/-0.6 mIU/ml vs 8.4+/-0.9 mIU/ml, p<0.05; 1.5% vs 7.8%, p<0.05). Therefore women with low day 3 serum inhibits-B concentrations demonstrate a poorer response to ovulation induction and are less likely to conceive a clinical pregnancy though ART relative to women with high day 3 inhibits-B and day 3 serum inhibin-B, in addition to a day 3 FSH, E2 and patient age, appears helpful in prediction in IVF-ET outcome.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean-
dc.publisher대한불임학회-
dc.relation.isPartOfKorean Journal of the Fertility and Sterility (대한불임학회잡지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.title보조 생식술 결과에 있어서 기저혈중 Inhibin-B의 예후인자로서의 유용성-
dc.title.alternativePrognostic Value of Day 3 Inhibin-B on Assisted Reproductive Technology Outcome-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Obstetrics and Gynecology (산부인과학교실)-
dc.contributor.googleauthor배상욱-
dc.contributor.googleauthor김진영-
dc.contributor.googleauthor이경술-
dc.contributor.googleauthor원종건-
dc.contributor.googleauthor이용주-
dc.contributor.googleauthor이지원-
dc.contributor.googleauthor장경환-
dc.contributor.googleauthor이병석-
dc.contributor.googleauthor박기현-
dc.contributor.googleauthor조동제-
dc.contributor.googleauthor송찬호-
dc.contributor.localIdA01793-
dc.contributor.localIdA02795-
dc.relation.journalcodeJ03749-
dc.contributor.alternativeNameBai, Sang Wook-
dc.contributor.affiliatedAuthor배상욱-
dc.contributor.affiliatedAuthor이병석-
dc.citation.volume24-
dc.citation.number2-
dc.citation.startPage217-
dc.citation.endPage224-
dc.identifier.bibliographicCitationKorean Journal of the Fertility and Sterility (대한불임학회잡지), Vol.24(2) : 217-224, 1997-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers

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