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Cowden's disease -a report on the first case in Korea and literature review-

Authors
 Lee HR  ;  Moon YS  ;  Yeom CH  ;  Kim KW  ;  Chun JY  ;  Kim HK  ;  Choi HS  ;  Kim DK  ;  Chung TS 
Citation
 JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.12(6) : 570-575, 1997 
Journal Title
 JOURNAL OF KOREAN MEDICAL SCIENCE 
ISSN
 1011-8934 
Issue Date
1997
MeSH
Adult ; Hamartoma Syndrome, Multiple/diagnosis* ; Hamartoma Syndrome, Multiple/epidemiology ; Humans ; Incidence ; Intestinal Polyps/pathology ; Keratoderma, Palmoplantar/pathology ; Korea/epidemiology ; Male ; Papilloma/pathology ; Thyroid Neoplasms/pathology ; Tongue Neoplasms/pathology
Abstract
Cowden's disease, or multiple hamartoma syndrome, is an uncommon condition with characteristic mucocutaneous lesions associated with abnormalities of the breast, thyroid, and gastrointestinal tract. We describe a 32-year-old man with oral mucosal papillomatosis and plantar hyperkeratosis as a definite case of Cowden's disease according to the criteria proposed by Salem and Steck. The patient also had a thyroid mass and numerous gastrointestinal polyps endoscopically. Histologically the polyps were hamartomatous or hyperplastic polyps. The oral papillary lesions were fibroepithelial polyps and the thyroid mass was a follicular adenoma. We review the literature on this entity and summarize the pertinent findings. To the best of our knowledge, this is the first documented case of Cowden's disease in a Korean.
Files in This Item:
T199701126.pdf Download
DOI
10.3346/jkms.1997.12.6.570
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Hogeun(김호근)
Lee, Hye Ree(이혜리)
Chung, Tae Sub(정태섭)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/177334
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