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분자유전학적으로 확진된 MELAS 증후군 환자의 수소 자기 공명 분광 분석 및 SPECT 소견
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김승민 | - |
dc.contributor.author | 남효석 | - |
dc.contributor.author | 이병인 | - |
dc.contributor.author | 최병옥 | - |
dc.date.accessioned | 2020-07-02T18:09:50Z | - |
dc.date.available | 2020-07-02T18:09:50Z | - |
dc.date.issued | 1998 | - |
dc.identifier.issn | 1225-7044 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/177203 | - |
dc.description.abstract | An eighteen-year-old girl presented recurrent partial and generalized seizures associated with the T-2 high signal intensities of MR brain imaging. Serum and CSF lactate levels were elevated. Muscle biopsy revealed 'ragged red fiber'. The diagnozed proton MR spectroscopy was performed on a GE 1.5 T SIGNA MRI/MRS system and analyzed by STEAM (Stimulated Echo Acquistition Method). 1H-MR spectrocopy demonstrated elevation of lactate contents and decrease of N-acetyl aspartate contents in the involved area. The Tc99m-ECD SPECT revealed multifocal decrease of perfusion in bilateral parietal, temporal and occipital lobe, especially right temporal and left occipital lobe. These features suggest that the pathology of brain lesions of MELAS syndrome may be sub-necrotic incomplete ischemic changes caused by metabolic derangement. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한신경과학회 | - |
dc.relation.isPartOf | Journal of the Korean Neurological Association (대한신경과학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 분자유전학적으로 확진된 MELAS 증후군 환자의 수소 자기 공명 분광 분석 및 SPECT 소견 | - |
dc.title.alternative | 1H-MR Spectroscopic and SPECT Findings in a Patient with MELAS Syndrome Confirmed by Molecular Genetic Analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurology (신경과학교실) | - |
dc.contributor.googleauthor | 최철희 | - |
dc.contributor.googleauthor | 김현숙 | - |
dc.contributor.googleauthor | 남효석 | - |
dc.contributor.googleauthor | 오원석 | - |
dc.contributor.googleauthor | 최병옥 | - |
dc.contributor.googleauthor | 김승민 | - |
dc.contributor.googleauthor | 이병인 | - |
dc.contributor.googleauthor | 김은숙 | - |
dc.contributor.googleauthor | 정은기 | - |
dc.contributor.localId | A00653 | - |
dc.contributor.localId | A01273 | - |
dc.contributor.localId | A02797 | - |
dc.contributor.localId | A04058 | - |
dc.relation.journalcode | J01836 | - |
dc.contributor.alternativeName | Kim, Seung Min | - |
dc.contributor.affiliatedAuthor | 김승민 | - |
dc.contributor.affiliatedAuthor | 남효석 | - |
dc.contributor.affiliatedAuthor | 이병인 | - |
dc.contributor.affiliatedAuthor | 최병옥 | - |
dc.citation.volume | 16 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 590 | - |
dc.citation.endPage | 596 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Neurological Association (대한신경과학회지), Vol.16(4) : 590-596, 1998 | - |
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